基本信息
views: 152
Career Trajectory
Bio
研究方向主要包括干细胞生物学和分子药理学。在干细胞定向分化方面,主要从事非甾体抗炎药物及糖皮质激素对干细胞骨向分化抑制作用的机制及预防措施研究。首次发现COX-2可经非前列腺素途径调节干细胞骨向分化,同时发现,维甲酸信号在预防COX-2抑制剂或糖皮质激素骨毒性方面具有重要作用。分子药理学方面,主要针对TGFβ信号和IGF信号筛选可能的潜在有效抗肿瘤药物靶点;通过建立超大容量sgRNA文库(大于2×107),分析肿瘤细胞的耐药机制。
Research Interests
Papers共 175 篇Author StatisticsCo-AuthorSimilar Experts
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Jie Zhang,Jinhai Jiang, Hang Liu, Shiyu Wang,Kaixin Ke,Siyuan Liu,Yue Jiang,Lu Liu,Xiang Gao,Baicheng He,Yuxi Su
Genes and Diseasesno. 3 (2024): 101075-101075
Kai-Xin Ke,Xiang Gao,Lu Liu,Wen-Ge He,Yue Jiang, Cheng-Bin Long, Gan Zhong,Zheng-Hao Xu,Zhong-Liang Deng,Bai-Cheng He,Ning Hu
Agingno. 9 (2024): 7870-7888
Journal of orthopaedic surgery and researchno. 1 (2023): 1-13
Current Stem Cell Research & Therapy (2023)
AMERICAN JOURNAL OF CANCER RESEARCHno. 3 (2023): 1137-1139
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Tissue engineering and regenerative medicineno. 5 (2023): 705-723
Regenerative Biomaterials (2023)
The international journal of biochemistry & cell biology (2023): 106476-106476
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