His main research interests are focused on understanding the factors that affect drug disposition and oral bioavailability with emphasis on transporters. Also, it involves studying the utility of physiological based pharmacokinetic modeling (PBPK) tools e.g. SimCYP in projecting drug disposition and drug-drug interaction liabilities in man for new molecular entities (NME). He is active member of the American Association of Pharmaceutical Scientists (AAPS) and serves on the executive committee of the physical pharmacy and biopharmaceutics and Northeastern Regional Discussion Group (NERDG) sections of AAPS. He has been invited speaker over 30 times at national and international conferences and meetings and has published over 100 papers in peer-reviewed Journals, book chapters and proceedings.