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个人简介
Group Leader, Membrane Protein Biology Group
International Centre for Genetic Engineering and Biotechnology
Aruna Asaf Ali Marg, New Delhi-110067. India
In the Membrane Protein Biology Group at ICGEB, New Delhi campus, we aim to understand a few biological processes and translate them for anti-cancer and anti-atherosclerosis therapy using target structure-based drug discovery. Our research focus is on 1) Dimorphic and bifunctional Dehydroascorbate reductases (DHARs)-cum-Chloride Intracellular Channels (CLICs) that recycle Vitamin-C as soluble enzymes and act as ion channels while membrane inserted, which are differentially expressed in various cancers, 2) Oxidized low-density lipoprotein (ox-LDL) receptor LOX1, responsible for atherosclerosis resulting in cardio- and cerebrovascular diseases, 3) Understanding the molecular basis of how traditional Indian medicine used for cardiovascular and cerebrovascular therapies works using modern biological tools.
研究兴趣
论文共 43 篇作者统计合作学者相似作者
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Biochemical and Biophysical Research Communications (2023): 135-141
Archives of biochemistry and biophysics (2023): 109603-109603
Current opinion in lipidologyno. 4 (2023): 147-155
bioRxiv (2022)
biorxiv(2021)
Acta Crystallographica Section A Foundations and Advancesno. a2 (2021): C39-C39
crossref(2021)
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作者统计
#Papers: 41
#Citation: 949
H-Index: 15
G-Index: 30
Sociability: 5
Diversity: 0
Activity: 1
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