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Bonci is known for his studies on the long-term effects of drug exposure on the brain.[6][7] Bonci's laboratory, in collaboration with Robert Malenka, was the first to demonstrate that drugs of abuse, such as cocaine, modify the strength of the connections between neurons.[8] This finding cast a new light on the phenomenon of drug addiction, as a process where maladaptive learning plays a role.[9] Subsequent studies have combined electrophysiological, optogenetic, molecular, and behavioral techniques to determine the long-term effects that are produced by chronic exposure to stress, cocaine or ethanol, with the goal of creating novel therapeutic avenues to decrease the devastating effects of these conditions.[10][11] In 2013, a study lead by Billy T. Chen,[12] provided rationale for the use of non-invasive brain stimulation, such as repeated Transcranial Magnetic Stimulation, in patients with cocaine use disorders. Clinical studies have indeed shown the potential of such technology in the treatment of cocaine use disorders.[13][14][15][16]; In Europe, publications by Dr. Bonci and collaborators have been used by the TMS company Mag Venture to obtain the European CE approval for treatment of addiction
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Journal of neural transmission (Vienna, Austria : 1996)no. 5 (2024): 505-508
Anna M. Klawonn,Michael Fritz,Silvia Castany,Marco Pignatelli,Carla Canal, Fredrik Similä,Hugo A. Tejeda, Julia Levinsson,Maarit Jaarola,Johan Jakobsson,Juan Hidalgo,Markus Heilig,
Current Opinion in Pharmacology (2021): 184-191
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 4 (2020): 1499
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