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职业迁徙
个人简介
I am an immunologist and a peptide biochemist, having spent 23 years across both disciplines. My research integrates peptidomics, proteomics, bioinformatics, biophysics, structural biology and functional assays to identify new targets of immune responses. Over my career I have made important contributions to understanding the role of antigen presentation, including the characterizing peptide epitopes involved in T cell recognition in several autoimmune diseases (e.g. Ankylosing Spondylitis, type 1 diabetes, rheumatoid arthritis and coeliac disease), drug hypersensitivity, cancer and infectious diseases. I am arguably one of Australia’s top proteomics researchers, and am well known for work that has highlighted a role for post-translationally modified antigens in autoimmunity and cancer. I have been instrumental in bringing new quantitative tools to immunological studies, in particular the use of multiple reaction monitoring to calculate the cell surface expression levels of specific MHC-peptide complexes both in vitro and in vivo. My lab is one of the first laboratories to adopt new data independent acquisition techniques and the first to apply it to quantitate antigen presentation at the protein and peptide epitope level.
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论文共 472 篇作者统计合作学者相似作者
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Amy Russell, Lee Henneken, Emma P. Halmos, Alexandra Olarte Guasca, Sri Ramarathiram, Mitchell McInerney,Pragalathan Apputhurai,Dean J. Clarke,Anthony Purcell,Jason A. Tye-Din
Gastroenterologyno. 5 (2024): S-728
Runqiu Song, Mariam Bafit,Kirsteen M Tullett,Peck Szee Tan,Mireille H Lahoud, Meredith O'Keeffe,Anthony W Purcell,Asolina Braun
Methods and protocolsno. 2 (2024): 20
Tejas Menon,Patricia T Illing,Priyanka Chaurasia,Hayley A McQuilten, Chloe Shepherd,Louise C Rowntree,Jan Petersen,Dene R Littler, Grace Khuu,Ziyi Huang,Lilith F Allen,Steve Rockman,
Hayley Goodson,Rebeca Kawahara,Sayantani Chatterjee, Gabriel Goncalves, Joshua Fehring,Anthony W. Purcell,Nathan P. Croft,Morten Thaysen-Andersen
Molecular & cellular proteomics : MCPno. 4 (2023): 100515-100515
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