Anne M. Andrews
教授
College of Physical Sciences
University of California, Los Angeles;Semel Institute for Neuroscience & Human Behavior, University of California, Los Angeles;Hatos Center for Neuropharmacology, University of California, Los Angeles;California NanoSystems Institute, University of California, Los Angeles
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At the NIMH, Andrews and her mentor, Dr. Dennis Murphy, discovered and characterized a novel serotonin neurotoxin, 2’-NH2-MPTP. Dr. Andrews was also instrumental in early studies on serotonin transporter-deficient mice. Andrews is a member of the Society for Neuroscience, American Chemical Society, and Society for Electroanalytical Chemistry. She has been the recipient of an NIH Fellows Award for Research Excellence, an Eli Lilly Outstanding Young Analytical Chemist Award, an American Parkinson’s Disease Association Research Award, and a Brain & Behavior Research Foundation (NARSAD) Independent Investigator Award. She is a fellow of the Collegium Internationale Neuropsychopharmacologicum and a Serotonin Club elected councilor. Recently, Dr. Andrews became Associate Editor for ACS Chemical Neuroscience.
At UCLA, Andrews leads efforts in basic and translational research on anxiety and depression, and at the nexus of nanoscience and neuroscience. Andrews’ interdisciplinary research team of neuroscientists, biologists, chemists, and engineers focuses on understanding how the serotonin system and particularly, the serotonin transporter, modulate neurotransmission to influence complex behaviors including anxiety, mood, stress responsiveness, and learning and memory. Genetic and pharmacologic mouse models and human genetic variants are studied to understand the molecular basis of serotonin system function associated with the etiology and treatment of mood and anxiety disorders. Key proteins (e.g., brain-derived neurotrophic factor) and neuronal architectures regulated by serotonin are also investigated. Nanomaterials are designed for fundamental studies on neurotransmitter recognition by native and nonnative binding partners (aptamers) and for the development of in vivo nanobiosensors and functionally directed proteomics.
At UCLA, Andrews leads efforts in basic and translational research on anxiety and depression, and at the nexus of nanoscience and neuroscience. Andrews’ interdisciplinary research team of neuroscientists, biologists, chemists, and engineers focuses on understanding how the serotonin system and particularly, the serotonin transporter, modulate neurotransmission to influence complex behaviors including anxiety, mood, stress responsiveness, and learning and memory. Genetic and pharmacologic mouse models and human genetic variants are studied to understand the molecular basis of serotonin system function associated with the etiology and treatment of mood and anxiety disorders. Key proteins (e.g., brain-derived neurotrophic factor) and neuronal architectures regulated by serotonin are also investigated. Nanomaterials are designed for fundamental studies on neurotransmitter recognition by native and nonnative binding partners (aptamers) and for the development of in vivo nanobiosensors and functionally directed proteomics.
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Cameron S Movassaghi,Anne Milasincic Andrews
Nature chemistryno. 4 (2024): 670-670
Cameron S. Movassaghi, Miguel Alcaniz Fillol,Kenneth T. Kishida,Gregory McCarty,Leslie A. Sombers,Kate M. Wassum,Anne Milasincic Andrews
Kyungae Yang, Noelle M. Mitchell, Saswata Banerjee, Zhenzhuang Cheng,Steven Taylor,Aleksandra M. Kostic, Isabel Wong, Sairaj Sajjath,Yameng Zhang,Jacob Stevens, Sumit Mohan,Donald W. Landry,
Scienceno. 6648 (2023): 942-948
Science Advancesno. 1 (2022)
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