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Listed below are some of the funded projects in Dr Bruce-Keller’s laboratory which are focused on brain inflammation in HIV and Alzheimer’s disease. In addition to these ongoing projects Dr Bruce-Keller is working on several new major research efforts. First, a project is underway to understand how diets high in fats and calories can detrimentally affect the brain, with a special emphasis on aging and age-related dementia. These efforts are a part of a multi-group effort at the PBRC and are the core of Program Project Grant proposal under development. Secondly, Dr. Bruce-Keller is working to understand how cognitive processes become impaired in setting of HIV infection, with specific emphases on opiate-based drugs and side effects of anti-retroviral therapies. Finally, Dr Bruce-Keller is working with others at the PBRC to establish an Institute for Dementia Research. This institute will include a longitudinal study of aging and dementia in individuals in Louisiana aged 60 and over, as well as include a platform for the identification of therapeutics for the prevention of dementia.
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OBESITYno. 8 (2020): 1386-1396
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