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The research of Anja Palmans develops along two lines. The first is aimed at mimicking multistep synthesis as it occurs in Nature. This allows for reduction of the need for purification procedures, and limits costs and waste in the production of complex organic molecules. To achieve this she evaluates the physical separation of multiple catalysts using synthetic polymers that fold into well-defined three-dimensional structures. This compartmentalization of catalysts is achieved through self-assembly of pendant recognition motifs in the polymers. The water-soluble catalysts thus formed are investigated for their application in complex media, with the aim to combine natural and non-natural catalytic reactions but also to catalytically activate prodrugs for cancer therapies. The second line concerns the control of the dynamic behavior of supramolecular copolymerizations, especially the exchange dynamics that represent the equilibrium between the monomer and the polymer. Copolymerizing supramolecular monomers with distinct differences in the dynamic behavior of their respective homopolymers could provide a handle to control the overall exchange dynamics of the supramolecular copolymer, and hereby their stability and function.
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论文共 256 篇作者统计合作学者相似作者
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Marle E. J. Vleugels, Rik Bosman, Piers H. da Camino Soligo,Stefan Wijker, Bence Feher, A. J. H. Spiering,Laura Rijns, Riccardo Bellan,Patricia Y. W. Dankers,Anja R. A. Palmans
CHEMISTRY-A EUROPEAN JOURNALno. 6 (2024): e202303361-e202303361
Linlin Deng,Alis R. Olea, Ana Ortiz-Perez,Bingbing Sun, Jianhong Wang, Silvia Pujals,Anja R. A. Palmans,Lorenzo Albertazzi
SMALL METHODSpp.e2301072-e2301072, (2024)
Ramkrishna Sarkar,Soumabrata Majumdar, Sierd Kuil, Jorg Mallens,Joost J. B. van Der Tol,Rint P. Sijbesma,Johan P. A. Heuts,Anja R. A. Palmans
JOURNAL OF POLYMER SCIENCEno. 13 (2023): 1335-1347
ChemPlusChemno. 7 (2023)
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Chemical communications (Cambridge, England)no. 36 (2023): 5407-5410
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