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Bio
Research Summary
Dr. De Marzo’s research focuses on prostate cancer, paying special attention to prevention. His research group has postulated that a common lesion often associated with inflammation—called proliferative inflammatory atrophy (PIA)—may represent a risk factor or precursor lesion to prostate cancer. This research has implications for prevention and chemoprevention of prostate cancer.
Dr Marzo’s laboratory is also using genetically engineered mouse models and cell culture systems to study the role of the MYC oncogene in prostate cancer cell neoplastic transformation and cell growth regulation. Since MYC is a key regulator of stem cells, these studies have direct implications for stem cell models of prostate cancer formation.
Additionally, the laboratory also has been leading efforts to apply novel biomarkers to human prostate tissues, to provide tissue banking for the prostate cancer research program, and to develop tissue microarrays and tissue microarray software.
Research Interests
Papers共 683 篇Author StatisticsCo-AuthorSimilar Experts
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Oluwademilade Dairo,Lia DePaula Oliveira, Ethan Schaffer,Thiago Vidotto,Adrianna A. Mendes,Jiayun Lu, Sophie Vo Huynh,Jessica Hicks,Adam G. Sowalsky,Angelo M. De Marzo, Corrine E. Joshu,Brian Hanratty,
crossref(2024)
medRxiv : the preprint server for health sciences (2024)
Radhika A. Patel,Erolcan Sayar,Ilsa Coleman,Martine P. Roudier,Brian Hanratty,Jin-Yih Low, Neha Jaiswal, Azra Ajkunic,Ruth Dumpit,Caner Ercan, Nina Salama,Valerie P. O'Brien,
Cancer Researchno. 6_Supplement (2024): 3043-3043
Oluwademilade Dairo, Lia De Paula Oliveira, Ethan Schaffer,Thiago Vidotto,Adrianna A. Mendes,Jiayun Lu, Sophie Vo Huynh,Jessica Hicks,Adam G. Sowalsky,Angelo M. De Marzo, Corrine E. Joshu,Brian Hanratty,
CANCER RESEARCH COMMUNICATIONSno. 1 (2024): 152-163
JCI Insightno. 24 (2023)
crossref(2023)
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crossref(2023)
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