Angelo D'Alessandro

Through high-throughput “omics” technologies, we are revealing recurring patterns in systemic responses to acute or chronic hypoxia. By focusing on red cell biology and transfusion medicine, we are increasingly appreciating shared molecular mechanisms driving systemic responses to hypoxia and oxidant stress in cancer, trauma/ hemorrhagic shock, I/R injury, sickle cell disease, ageing and inflammation, mammalian hibernation, and pulmonary hypertension.