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个人简介
I obtained my PhD in Biochemistry and Molecular Biology from Paris Sud 11 University in 2005. During my PhD in Ralf Jocker’s Team at Cochin Institute in Paris, my work consisted to investigating the functional consequences of melatonin receptors heterodimerization and to searching the function of orphan G-Protein Coupled Receptor (GPCR) GPR50. This work was the first demonstration that orphan GPCR can modulate the function of GPCR with identified ligand and known function.
In 2006, I jointed the Françoise Bachelerie’s Team at Pasteur Institute in Paris as post-doctoral fellow. During this period, I’m interested to the interactions between the chemokine CXCL12/SDF-1 and it’s receptors CXCR4 and ACKR3/CXCR7 in a physiological and in WHIM syndrome, a rare and inherited chemotactic disorder determined by a pathologic gain of function of CXCR4 in response to CXCL12.
In 2011, I have a permanent position as associate professor at the University Sorbonne Paris Nord (Chaire Mixte Inserm-University). I worked at INSERM U1148 (Laboratory of Vascular Translational Science) at Bichat hospital in Paris where I investigated the role of High Density Lipids (HDL) receptors in vasculo-protective effects of HDL on Blood-Brain Barrier in ischemic sroke (Olivier Meilhac Team).
Since 2016, I work in the Jean-Sebastien Silvestre ’s Team at Paris Cardiovascular Research Center (PARCC / Georges Pompidou European Hospital), and I interested to the role of CXCL12 isoforms and ACKR3/CXCR7 receptor in post-ischemic remodeling and cardiac regeneration after myocardial infarction by combining genetic approaches in the mouse with a wide range of cell and molecular biology methods.
研究兴趣
论文共 46 篇作者统计合作学者相似作者
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Journal of the American College of Cardiologyno. 7 (2022): 632-647
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作者统计
#Papers: 45
#Citation: 2449
H-Index: 22
G-Index: 45
Sociability: 5
Diversity: 0
Activity: 0
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