基本信息
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职业迁徙
个人简介
Research Interests:
Research interests are G-Protein Coupled Receptor (GPCR), activation and regulation by drugs. The mechanisms of GPCR activation are being explored via: (i) investigating the role of the extracellular loops in regulating the activation of GPCRs and as a site of interaction with allosteric modulator drugs in adrenergic, inflammatory (C5aR) and taste receptors (ii) a drug discovery program which is developing urogenital selective α1-adrenoceptor antagonists for the treatment of prostate diseases and adrenoceptor modulators for Rett syndrome, seizure disorders and other neurological conditions.
Broad Research Areas:
Pharmacology, Molecular Structure & Drug Design
Society Memberships & Professional Activities:
ASCEPT
Specific Research Keywords:
G-protein Coupled Receptors, Drug Discovery, Molecular Mechanisms, Pharmacology, Cell Biology, Adrenoceptor, Complement Receptor 5a, Taste Receptors
Research interests are G-Protein Coupled Receptor (GPCR), activation and regulation by drugs. The mechanisms of GPCR activation are being explored via: (i) investigating the role of the extracellular loops in regulating the activation of GPCRs and as a site of interaction with allosteric modulator drugs in adrenergic, inflammatory (C5aR) and taste receptors (ii) a drug discovery program which is developing urogenital selective α1-adrenoceptor antagonists for the treatment of prostate diseases and adrenoceptor modulators for Rett syndrome, seizure disorders and other neurological conditions.
Broad Research Areas:
Pharmacology, Molecular Structure & Drug Design
Society Memberships & Professional Activities:
ASCEPT
Specific Research Keywords:
G-protein Coupled Receptors, Drug Discovery, Molecular Mechanisms, Pharmacology, Cell Biology, Adrenoceptor, Complement Receptor 5a, Taste Receptors
研究兴趣
论文共 69 篇作者统计合作学者相似作者
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BRITISH JOURNAL OF PHARMACOLOGY (2023): 694-695
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BRITISH JOURNAL OF PHARMACOLOGY (2023): 628-628
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BRITISH JOURNAL OF PHARMACOLOGY (2023): 699-700
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Nature Chemical Biologyno. 4 (2021): 383-386
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