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Our programme to use the power of systematic genetics in C. elegans to understand the basic principles underlying human Mendelian disorders combines quantitative biology, computational biology, and human genetics. We believe it addresses one of the most fundamental aspects of human genetic disease — not to identify which mutations affect the health of humans in general, but to understand the effect of any mutation on a single affected human.
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Papers共 97 篇Author StatisticsCo-AuthorSimilar Experts
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Nature communicationsno. 1 (2024): 3367-3367
bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2021)
bioRxiv (Cold Spring Harbor Laboratory)pp.1-31, (2020)
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