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个人简介
Research in the Dlugosz lab is centered on defining the functions of deregulated signaling pathways in skin biology and cancer, with a major emphasis on basal cell carcinoma (BCC) and Merkel cell carcinoma (MCC). Using genetically-engineered mouse models developed in his laboratory, Dr. Dlugosz helped establish a central role for deregulated Hedgehog signaling in BCC initiation, expansion, and maintenance; defined critical interactions between Hedgehog and other signaling pathways in tumorigenesis; and elucidated the importance of cell of origin, timing of oncogene activation, and magnitude of Hedgehog signaling as key determinants of skin tumor phenotype. In more recent studies, he has been investigating the molecular basis of MCC. Dr. Dlugosz has authored over 125 publications, including peer-reviewed papers, review articles, commentaries, and book chapters.
研究兴趣
论文共 41 篇作者统计合作学者相似作者
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Monique E. Verhaegen,Doris Mangelberger,Paul W. Harms,Markus Eberl,Dawn M. Wilbert, Julia Meireles, Christopher K. Bichakjian,Thomas L. Saunders,Sunny Y. Wong,Andrzej A. Dlugosz
crossref(2023)
Monique E Verhaegen,Paul W Harms, Julia J Van Goor,Jacob Arche,Matthew T Patrick,Dawn Wilbert, Haley Zabawa,Marina Grachtchouk,Chia-Jen Liu,Kevin Hu,Michael C Kelly,Ping Chen,
Anna Shirazyan,Haeyoung Park, Ariell M. Joiner, Justine Ra,Melissa S. Kim,Archana Kumari,Nicole E. Franks,Tien Peng,Robert K. Bradley,Charlotte M. Mistretta,Andrzej A. Dlugosz,Benjamin L. Allen
crossref(2022)
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