基本信息
浏览量:5
职业迁徙
个人简介
T and B lymphocytes are key components of vertebrate immune systems. They form richly structured and highly interactive communities that provide protection against infection while maintaining tolerance to innocuous antigens. They also encode immunological memory, responding rapidly and potently to previously encountered antigens. Our research integrates theoretical and computational tools with more traditional experimental approaches to study multiple aspects of lymphocyte dynamics. Our aim is to develop a mechanistic understanding of the rules underlying lymphocyte development, homeostasis, and their trajectories in response to antigen challenge. Our philosophy is to confront and break models with data to search for robust and quantitative explanations of immunological phenomena. Our current interests relate to the population dynamics of circulating lymphocytes, with particular focus on the impact of age on their persistence and function; the ecology of tissue-resident memory T cells; the recovery of lymphocyte subsets following hematopoietic stem cell transplantation; and the responses of HIV-infected infants to antiretroviral therapy.
研究兴趣
论文共 69 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Nature Communicationsno. 1 (2024): 1-20
M. Elise Bullock,Thea Hogan,Sinead Morris,Maria Nowicka, Christiaan van Dorp,Andrew J. Yates,Benedict Seddon
biorxiv(2023)
引用0浏览0引用
0
0
Immunityno. 8 (2023): 1894-+
semanticscholar(2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn