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个人简介
McKenzie's research investigates how the innate immune system and adaptive immune system protect the body from infection, but can also lead to inflammation and pathology. He has defined and characterised how biological networks orchestrate responses to pathogens and how dysregulation of these biological pathways can lead to diseases such as asthma and allergy.
His identification of the cytokine Interleukin 13 and the subsequent unearthing of its central role in allergic asthma led to his discovery of type-2 innate lymphoid cells (ILC2). These cells secrete large quantities of cytokines and represent a new druggable biological target for intervention in inflammation and infection.
His identification of the cytokine Interleukin 13 and the subsequent unearthing of its central role in allergic asthma led to his discovery of type-2 innate lymphoid cells (ILC2). These cells secrete large quantities of cytokines and represent a new druggable biological target for intervention in inflammation and infection.
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NATURE REVIEWS IMMUNOLOGYno. 4 (2024): 294-302
JCO ONCOLOGY PRACTICEno. 2 (2024): 157-159
Free neuropathology (2024)
NATURE IMMUNOLOGY (2023)
Gabriel A Marx,Justin Kauffman,Andrew T McKenzie,Daniel G Koenigsberg, Cory T McMillan,Susan Morgello,Esma Karlovich,Ricardo Insausti,Timothy E Richardson,Jamie M Walker,Charles L White, Bergan M Babrowicz,
Acta neuropathologicano. 6 (2023): 785-802
Emma Sturgill, J. N. Srivastava, J Correia, Cooper S. Schumacher, Daniel J. Luckett,Cesar A. Perez,Judy S. Wang,Stephen G. Divers,Babar Bashir,Jennifer M. Johnson,Valerie M. Jansen,Andrew J. McKenzie,
Cancer Researchno. 7_Supplement (2023): 921-921
Frontiers in aging neuroscience (2023): 1153251
Elisa Balmas, Batika MJ Rana,Russell S Hamilton,Norman Shreeve,Jens Kieckbusch,Irving Aye,Delia A Hawkes, Sophie Trotter,Jorge López-Tello,Hannah EJ Yong, Salvatore Valenti, Amanda N Sferruzi-Perri,
biorxiv(2023)
Margaret M Krassner,Justin Kauffman,Allison Sowa, Katarzyna Cialowicz, Samantha Walsh,Kurt Farrell,John F Crary,Andrew T McKenzie
Free neuropathology (2023)
Nature communicationsno. 1 (2023): 7201-11
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