Andrew Lees - Fina BioSolutions LLC | 人才画像

基本信息

Career Trajectory

Bio

Andrew Lees currently works at Fina BioSolutions LLC. Andrew does research in Biotechnology. Their current project is 'Clinical grade CRM197 carrier protein'. I work on conjugate vaccine development, especially on the chemistry of conjugate vaccine synthesis. I am the developer of CDAP conjugation chemistry and am still working on improving the process.

Research Interests

Papers共 80 篇Author StatisticsCo-AuthorSimilar Experts

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Detecting Residual Chronic Salmonella Typhi Carriers on the Road to Typhoid Elimination in Santiago, Chile, 2017-2019

Rosanna M. Lagos,Michael J. Sikorski,Juan Carlos Hormazabal,Alda Fernandez,Sergio Duarte,Marcela F. Pasetti,David A. Rasko,Ellen Higginson,Joseph Nkeze,Irene N. Kasumba,Gordon Dougan,Mailis Maes,Andrew Lees,Sharon M. Tennant,Myron M. Levine

The Journal of Infectious Diseases (2023)

Cited2Views0WOSBibtex

Monomeric Crystal Structure of the Vaccine Carrier Protein CRM197 and Implications for Vaccine Development

D. Travis Gallagher, Natalia Oganesyan,Andrew Lees

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS（2023）

Cited3Views0WOSBibtex

Genetically Detoxified Tetanus Toxin As a Vaccine and Conjugate Carrier Protein

Min-Ju Chang,Morgane Ollivault-Shiflett,Richard Schuman,Son Ngoc Nguyen,Igor A. Kaltashov,Cedric Bobst,Shalini P. Rajagopal,Amanda Przedpelski,Joseph T. Barbieri,Andrew Lees

Vaccine（2022）

Cited9Views0WOSBibtex

Enhancing Polysaccharide Immunity through Intranasal Immunizations

Kevin Trabbic,Shyamala Ganesan,Ali Fattom,Andrew Lees,Vira Bitko

bioRxiv (Cold Spring Harbor Laboratory)（2022）

Cited0Views0Bibtex

Multisite Study of the Prevalence of Salmonella Typhi Carriers among 2,307 Persons of Two Different Age Groups (≥55 and 18-34 Years) Undergoing Cholecystectomy in Santiago, Chile, 2017-2019

Rosanna M. Lagos,Catterina Ferreccio,Juan Carlos Hormazábal,Michael Sikorski,Sergio Duarte,Ellen Higginson,Sharon M. Tennant, Marcella Pasetti,Marcelo B. Sztein,Joseph Nkeze,Irene N. Kasumba,William C. Blackwelder,Paz Cook,Alda Fernandez,Gordon Dougan,Raphael Simon,Andrew Lees,J. Kathleen Tracy,Paula Daza, Pablo Mena, Julio Yarmuch, Diego Valenzuela, Gerardo Thonet,Lorenzo Gonzalez Palacios,Gloria Aguayo,Eduardo Viñuela,Myron M. Levine

SSRN Electronic Journal (2022)

Cited1Views0Bibtex

Harnessing Galactose Oxidase in the Development of a Chemoenzymatic Platform for Glycoconjugate Vaccine Design

Jeremy A. Duke,Amy Paschall,John Glushka,Andrew Lees,Kelley W. Moremen,Fikri Y. Avci

Journal of Biological Chemistry（2021）

Cited11Views0WOSBibtex

Activation and Conjugation of Soluble Polysaccharides Using 1-Cyano-4-dimethylaminopyridine Tetrafluoroborate (CDAP)

Andrew Lees, James Zhou

Journal of Visualized Experiments (2021)

Cited3Views0WOSBibtex

Activation And Conjugation Of Soluble Polysaccharides Using 1-Cyano-4-Dimethylaminopyridine Tetrafluoroborate (Cdap) (July, 10.3791/6470, 2021)

Andrew Lees, James Zhou

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2021)

Cited0Views0Bibtex

Engineered E. coli with an oxidative cytoplasm and efficient cleavage of N-terminal methionine

Andrew Lees,Morgane Ollivault-Shiflett, Min-Ju Chang

crossref（2021）

Cited0Views0Bibtex

Activation of Soluble Polysaccharides with 1-Cyano-4-dimethylaminopyridine Tetrafluoroborate (CDAP) for Use in Protein–Polysaccharide Conjugate Vaccines and Immunological Reagents. III Optimization of CDAP Activation

Andrew Lees,Jackson F. Barr,Samson Gebretnsae

Vaccines（2020）

Cited18Views0WOSBibtex

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