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Investigations into VDJ recombination ability in patients with severe immunodeficiency and sensitivity to ionising radiation. We have established a fibroblast assay to measure VDJ recombination in vitro and are looking at VDJ recombination in a family with severe T cell immunodeficiency. We aim to utilise this assay with other patients with impaired VDJ recombination to examine fidelity.
A study to determine whether preterm infants can make a protective antibody response to the pneumococcal serotypes in Prevenar conjugate heptavalent pneumococcal vaccine following the national UK immunisation schedule:
This is a multicentre clinical study with Alan Fenton in Neonatolgy to assess the efficacy of a new conjugated pneumococcal vaccine in pre-term neonates. This has established a multivalent pneumococcal ELISA assay in Newcastle, and will compliment some of the current research into the nature of the pneumococcal antibody response.
A study to determine whether preterm infants can make a protective antibody response to the pneumococcal serotypes in Prevenar conjugate heptavalent pneumococcal vaccine following the national UK immunisation schedule:
This is a multicentre clinical study with Alan Fenton in Neonatolgy to assess the efficacy of a new conjugated pneumococcal vaccine in pre-term neonates. This has established a multivalent pneumococcal ELISA assay in Newcastle, and will compliment some of the current research into the nature of the pneumococcal antibody response.
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Bloodno. 24 (2024): 2504-2516
Andrew J Fisher,Michael White,Nicola Goudie, Anneka Kershaw, Julia Phillipson,Michelle Bardgett,Joanne Lally, Alex Bevin-Nicholls,Thomas Chadwick,Andrew Bryant,Sian Russell, Hesther Smith,
BMJ Open Respiratory Researchno. 1 (2024)
BMJ Open Respiratory Researchno. 1 (2024)
Rui Chen, Elena Lukianova,Ina Schim van der Loeff,Jarmila Stremenova Spegarova,Joseph D P Willet,Kieran D James,Edward J Ryder,Helen Griffin,Hanna IJspeert,Akshada Gajbhiye,Frederic Lamoliatte, Jose L Marin-Rubio,
Science immunologyno. 95 (2024): eade5705-eade5705
JOURNAL OF CLINICAL MEDICINEno. 4 (2024): 1092
The EBMT Handbookpp.809-817, (2024)
Blood (2024)
Andrew J Fisher,Michael White,Nicola Goudie, Anneka Kershaw, Julia Phillipson,Michelle Bardgett,Joanne Lally, Alex Bevin-Nicholls,Thomas Chadwick,Andrew Bryant,Sian Russell, Hesther Smith,
BMJ open respiratory researchno. 1 (2024)
Muskan Israni, Eliska Alderson, Nizar Mahlaoui,Laura Obici,Linda Rossi-Semerano,Helen Lachmann,Mojca Zajc Avramovič,Aurelien Guffroy,Virgil Dalm, Rachel Rimmer,Leire Solis, Carlota Villar,
crossref(2024)
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