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个人简介
After completing my undergraduate degree in Biochemistry at The University of Sheffield, I moved to The University of Glasgow where I undertook Masters and PhD projects with Professor Gwyn Gould, in the areas of membrane trafficking and cytokinesis. I gained my first postdoctoral position at the BC Cancer Research Centre, Vancouver where I worked with Professor Shoukat Dedhar on centrosome cell biology in cancer cells. Subsequently I returned to the UK and to The University of Liverpool where I held postdoctoral positions with Dr Steve Royle (now at University of Warwick) and Professor Judy Coulson. With Steve I investigated clathrin coated vesicle formation in mitosis. During my time with Judy, we discovered a key role for the deubiquitylase USP15 in regulation of genomic stability and subsequently studied the role of deubiquitylases in centrosome biology, particularly centrosome clustering in cancer cells. Collaborations with experts in Uveal Melanoma (Sarah Coupland) and radiation biology (Jason Parsons), enabled me to start my own independent research directions, before being appointed as North West Cancer Research Lecturer at the University of Lancaster in March 2018. Here I am interested in cancer cell biology, particularly how cancer cells cope with excess centrosomes and how this represents a therapeutic target. I continue to study how deubiquitylases and radiation therapy affects cancer cell division. I am currently using models of breast cancer and uveal melanoma in my research.
研究兴趣
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Cold Spring Harbor protocolsno. 11 (2014): 1188-91
Cold Spring Harbor protocolsno. 11 (2014): 1184-7
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#Papers: 32
#Citation: 1837
H-Index: 20
G-Index: 32
Sociability: 5
Diversity: 0
Activity: 0
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