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Bio
Research Summary
My research is concerned with the embryonic mechanisms underlying central nervous system development and congenital disorders. The laboratory is known internationally for its expertise in animal models of birth defects, particularly neural tube defects (e.g. spina bifida). It is the first lab to take a potential new therapy for a birth defect, worked out in mouse models (i.e. inositol for prevention of folic acid-resistant neural tube defects), and to apply it to human pregnancy through a pilot clinical trial, the PONTI study (Br J Nutr, 2016, 115, 974-83). A positive outcome of a full-scale trial would be the first innovation in primary prevention of a significant human birth defect since the research on folic acid in the late 1980s. My research team is supported by funding from the Wellcome Trust, Medical Research Council, SPARKS (Sport Aiding Medical Research in Kids), Newlife Foundation for Disabled Children and the Bo Hjelt Spina Bifida Foundation.
Research Interests
Papers共 369 篇Author StatisticsCo-AuthorSimilar Experts
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Abigail R Marshall, Andrea Krstevski, Henry Croswell, Rahul Shah,Eirini Maniou,Nicholas DE Greene,Andrew J Copp,Gabriel L Galea
biorxiv(2024)
Molecular genetics and metabolismno. 3 (2024): 108496-108496
FASEB JOURNALno. 11 (2024): e23738-e23738
Cells & development (2023): 203840-203840
Development (Cambridge, England) (2023)
Methods in molecular biology (Clifton, N.J.) (2023): 147-162
Disease Models & Mechanismsno. 3 (2023)
Chloe Santos, Ailish Murray,Abigail R. Marshall, Kate Metcalfe, Priyanka Narayan,Sandra C. P. de Castro,Eirini Maniou,Nicholas D. E. Greene,Gabriel L. Galea,Andrew J. Copp
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Author Statistics
#Papers: 370
#Citation: 19503
H-Index: 73
G-Index: 130
Sociability: 7
Diversity: 3
Activity: 51
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