基本信息
views: 17
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Research description
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes (writers) responsible. I have a keen interest in identifying protein domains that specifically bind (readers) to modified histones. This information has been used to enable the development of small molecule inhibitors (to both writers and readers).
More recently, my focus has switched to the analysis of post-transcriptional RNA modifications and the relevant enzymes. Ultimately, I hope to be able to use the knowledge gained to develop novel anti-cancer therapeutic compounds.
I have spent the last three decades generally messing around with chromatin with a special focus on histones and their modifications. My research has focused on identifying novel histone modifications together with characterization of the enzymes (writers) responsible. I have a keen interest in identifying protein domains that specifically bind (readers) to modified histones. This information has been used to enable the development of small molecule inhibitors (to both writers and readers).
More recently, my focus has switched to the analysis of post-transcriptional RNA modifications and the relevant enzymes. Ultimately, I hope to be able to use the knowledge gained to develop novel anti-cancer therapeutic compounds.
Research Interests
Papers共 132 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
crossref(2023)
crossref(2023)
NUCLEIC ACIDS RESEARCHno. 15 (2023): 7709-7713
crossref(2023)
CANCERSno. 1 (2022): 151
Natureno. 7860 (2021): 597-601
Nature Microbiologyno. 1 (2021): 154-168
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn