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个人简介
The focus of our work is Dendritic cells and Monocytes. Dendritic cells are the most important antigen-presenting cell type throughout the immune system and develop from dedicated precursors in the bone marrow. During their development Dendritic cells acquire functional specialization and tissue-specific adaption and we are investigating how these processes are regulated on a transcriptomic and functional level. Additionally, we are investigating the functional and development processes leading to the functional specialization of Monocytes during health and disease. To tackle these important questions we are using cutting edge technologies such as single-cell mRNA sequencing, advanced flow cytometry and in vivo differentiation assays, which allow us for the first time to draw a global picture of these complex developmental processes.
研究兴趣
论文共 78 篇作者统计合作学者相似作者
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Lea Seep,Stephan Grein, Iva Splichalova, Danli Ran, Mickel Mikhael,Staffan Hildebrand, Mario Lauterbach, Karsten Hiller, Dalila Juliana Silva Ribeiro,Katharina Sieckmann, Ronja Kardinal,Hao Huang,
biorxiv(2024)
Hongkui Xiao,Isabel Ulmert, Luisa Bach,Johanna Huber, Hamsa Narasimhan,Ilia Kurochkin,Yinshui Chang, Signe Holst, Urs Mörbe, Lili Zhang,Andreas Schlitzer, Carlos-Filipe Pereira,
Nature communicationsno. 1 (2024): 3554-3554
Amir Hossein Kayvanjoo,Iva Splichalova, David Alejandro Bejarano,Hao Huang, Katharina Mauel,Nikola Makdissi, David Heider, Hui Ming Tew,Nora Reka Balzer, Eric Greto,Collins Osei-Sarpong,Kevin Baßler,
H Theobald, D A Bejarano, N Katzmarski, J Haub,J Schulte-Schrepping,J Yu,K Bassler, A L Ament,C Osei-Sarpong, F Piattini, L Vornholz, W T'Jonck,
Jiangyan Yu, Jake Thomas, Jessica Haub,Carmen Pizarro, Miaomiao Zhang,Leonie Biener,Matthias Becker,Lili Zhang, Theodoros Kapellos,Wolfgang Schulte,Joachim Schultze,Jan Hasenauer,
biorxiv(2023)
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Immunityno. 8 (2023): 1761-+
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NATURE IMMUNOLOGYno. 2 (2023): 371-372
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