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The common theme to his research projects has been the investigation of medically relevant enzymes with interesting chemical properties, such as complex multifunctional systems and proteins performing unusual catalytic functions. The core of the research activity is represented by X-ray crystallography, employed to study protein three-dimensional structures. This is, however, complemented by other approaches such as site-directed mutagenesis, analysis of enzyme kinetics and computational chemistry. The laboratory has received funding by national and international agencies, including the National Institute of Health (USA), the European Community and pharmaceutical companies.
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Callum R. Nicoll, Laura Alvigini,Andrea Gottinger, Domiziana Cecchini,Barbara Mannucci,Federica Corana,María Laura Mascotti,Andrea Mattevi
Nature Catalysisno. 2 (2024): 148-160
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PROSTATE (2024)
A Mandl, S Jasmine, Teg Krueger,R Kumar,I M Coleman,S L Dalrymple,L Antony,D M Rosen, Y Jing,B Hanratty,R A Patel,L Jin-Yih,
bioRxiv : the preprint server for biology (2024)
Chembiochem : a European journal of chemical biologyno. 24 (2023): e202300588-e202300588
Free Radical Biology and Medicine (2023): 39-39
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Current opinion in structural biology (2023): 102669-102669
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Joana Reis,Christoph Gorgulla,Marta Massari,Sara Marchese,Sergio Valente,Beatrice Noce, Lorenzo Basile, Ricarda Törner, Huel Cox III,Thibault Viennet,Moon Hee Yang, Melissa M. Ronan,
Nature chemical biologyno. 12 (2023): 1540-1550
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Springer eBookspp.521-534, (2023)
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Sandhya Malla,Kanchan Kumari, Carlos Martinez-Gamero,Carlos A. García-Prieto,Stephanie Stransky, Jonatan Caroli,Damiana Álvarez-Errico, Paulina Avovome Saiki,Weiyi Lai,Cong Lyu,Jonathan D. Gilthorpe,Hailin Wang,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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