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个人简介
In 2013 I obtained my master’s degree in Chemistry and Pharmaceutical Technology at the University of Milan after one year of internship in the lab of Prof. Cristiano Rumio at Humanitas Research Hospital (Milan, Italy), where I studied the anti-inflammatory effects of synthetic ligands for the sodium-glucose transporter SGLT1 in small intestine of mice that were treated with doxorubicin.
Then I moved to Israel for my postgraduate studies in the laboratory of Prof. Michael Blank (Bar-Ilan University) where I completed my PhD on the investigation of the pleiotropic roles of SMURF2 (an E3 ubiquitin ligase) in carcinogenesis, DNA damage response and genomic instability.
In 2018, I joined Andreas Bikfalvi’s lab where I extended my approach to cancer biology (i.e. from cancer cell to the surrounding microenvironment). Here, using a murine model of renal cell carcinoma (RCC), we revealed distinct signatures of tumor aggressiveness and identified potential biomarkers predictive for therapeutic response in RCC patients (Cooley LS et al. Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression. Mol Cancer 20, 136 - 2021). At the moment, I am now leading a project dealing with the investigation of the role of one of such biomarkers in the regulation of the tumor microenvironment of RCC, with a particular focus on tumor associated macrophages.
研究兴趣
论文共 17 篇作者统计合作学者相似作者
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CANCER RESEARCH COMMUNICATIONSno. 7 (2024): 1702-1714
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crossref(2023)
Cellular and molecular life sciences : CMLSno. 5 (2022): 237-237
CANCER RESEARCHno. 12 (2022)
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Cancer Researchno. 12_Supplement (2022): 3140-3140
Interrogating the Immune Landscape of Cancerno. 1 (2022)
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作者统计
#Papers: 17
#Citation: 121
H-Index: 5
G-Index: 9
Sociability: 4
Diversity: 1
Activity: 6
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