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Niels H. Andersen,Professor of Chemistry
Ph.D. Northwestern University, 1967.Research Interests
Research in the Andersen group focuses on both the fundamental thermodynamics and structural features associated with biorecognition phenomena and practical applications in drug and protein design. The primary biophysical tools employed are spectroscopic: NMR determinations of polypeptide structure and dynamics, IR- and fluorescence-monitored T-jump kinetics for folding pathways, CD studies of the melting of secondary and tertiary structure. Drug design efforts are supported by NMR structural data for protein hormones and enzymes for key steps required for the viability of bacteria. Active programs in mutant protein over-expression, peptide synthesis, and combinatorial synthesis of small molecule inhibitor libraries support this effort. Illustrative projects are briefly outlined in the following paragraphs.
Research Interests
Papers共 558 篇Author StatisticsCo-AuthorSimilar Experts
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MATERIALSno. 5 (2024): 994
European journal of endocrinologyno. 6 (2024): G53-G151
Clinical endocrinologyno. 6 (2024): 515-526
The Lancet Regional Health - Europe (2024): 100789-100789
Maria W. Pedersen,Kirsten Duch, Filip L Lindgren, Nils L.O. Lundgren,Bhupendar Tayal,Andreas Hagendorff,Gorm B. Jensen,Tor Biering-Sørensen,Peter Schnohr,Rasmus Møgelvang,Nis Høst,Kristian Kragholm,
Casper Falster,Maja Hellfritzsch, Thomas Agerbo Gaist,Mikkel Brabrand,Rahul Bhatnagar,Mads Nybo,Niels Holmark Andersen,Gro Egholm
The Lancet. Haematologyno. 11 (2023): e922-e935
American Heart Journal Plus: Cardiology Research and Practice (2023): 100240-100240
Scientific Reportsno. 1 (2023): 1-10
Molecular pharmaceuticsno. 6 (2023): 2853-2863
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Author Statistics
#Papers: 541
#Citation: 17423
H-Index: 64
G-Index: 114
Sociability: 7
Diversity: 1
Activity: 3
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