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Bio
Ana Milhinhos has a PhD in Molecular Biology (ITQB-NOVA, 2013) and a degree in Plant Biology (2003). Her research focus on studying the genetic and molecular basis of secondary growth in trees and model plants, with emphasis on vascular cambium and cork cambium activity and her CV includes description of some of the few know regulators of secondary growth. She has experience with a large spectrum of trees and secondary growth model systems, such as maritime pine, cork oak, Populus and Arabidopsis. Since then, she has been a post-doc at H. Touminen Lab at UPSC (Umeå, SE), dedicated to molecular aspects of wood formation. From 2015-2017, she was awarded the prestigious Marie Sklodowska-Curie Individual Fellowship Grant to work at Plant Sciences, U. Oxford (UK; mentors: Javier Agusti, Liam Dolan), to study the natural variation of secondary growth through GWAS, in Arabidopsis. In 2018, Ana was awarded a CEEC-IND/2017 salary grant in a competitive call to sponsor her return to PT and start building her own research lines (ITQB-NOVA) and works at ForGen Lab, taking advantage of her large expertise gained throughout her career and internationalization, as shown by publications in high ranked journals, such as Plant J (Milhinhos et al 2013), J Exp Bot (Miguel et al 2016) or PNAS (Milhinhos et al 2019).
Career path statement: Deciphering molecular mechanisms and developmental aspects of tree biology, namely secondary growth. I am interested in finding the actual functional role of genes for the secondary growth trait. There has been a immense amount of genomic and transcriptomic data produced and unveiled in the past years, however the translation of this information to agro-forestry has been lacking. My main interest is understanding and translating this information into concrete valuable information for farmers and stakeholders to use. I recently returned to Portugal, sponsored by a CEEC-IND/2017 salary grant awarded in a competitive FCT call, that has just started and am establishing my own lines of research at Green-IT (ITQB-NOVA) & BioISI (FCUL).
In recent years, I worked at:
(1) University of Oxford (Oxford, UK; Sep/2015-Dec/2017) - Marie Sklodowska-Curie individual fellow (PIs: Javier Agusti/Liam Dolan), resulting in 2 impactful publications (Milhinhos et al 2019; Thamm et al 2019);
(2) UPSC (Umeå, Sweden; Oct-Dec/2013 & Jan-Aug/2015) - Invited Post-Doc Researcher & later Senior post-Doc Researcher involved in BioImprove & FuncFiber projects to enhance wood properties for Biomass (PI: H Touminen);
(3) iBET (Oeiras, PT; Jan-Dec/2014) - post doc for ProCoGen European project (PI: CM Miguel). I collaborated with A. Miguel resulting in authorships in J Exp Bot (Miguel et al 2016) and with A. Rodrigues in Scientific Reports (Rodrigues et al 2019);
(4) ITQB-NOVA (Oeiras, PT; Oct/2008-Jul/2013) - PhD studies (Milhinhos, 2013; Advisor: CM Miguel), describing a safeguard negative feedback loop mechanism specific to xylem to maintain thermospermine homeostasis, involving auxin and HD-ZIPIIIs, resulting in 2 publications (Plant J & Plant Cell Rep).
(5) CRAG (Barcelona, SP; Oct2007-Jul2008 - Effect of brassinosteroids and HD-Zip III TFs functions in root meristem and vascular development (Advisor: Dr. A. C.-Delgado).
(6) ITQB-NOVA undergraduate, generated in vitro cultures of cork oak (Q. suber) from adult provenance and conducted histochemical and histological studies to somatic embryogenesis of maritime pine (P. pinaster) (Milhinhos, 2003; Advisors: M. Margarida Oliveira & C. Pinto Ricardo, Oeiras, PT).
I have ongoing collaborations with Javi Agusti and Miguel A. Blazquez (IBMCP-UPV; Valencia, SP); Hannele Tuominen (UPSC/SLU, Umeå, SE), Cristina Silva Pereira (ITQB-NOVA, PT), Augusta Costa (CENSE-INIAV, PT), Pedro M. Costa (UCIBIO, FCT-UNL,PT). I have high impact publications, international oral presentations, poster communications, experience in supervising, tutoring & mentoring several PhD, Master, grad and understudents at Oxford, ITQB, iBET & FCUL.
Area of scientific activity:
My scientific activity focuses on the molecular aspects of secondary growth in woody species. As the increase in thickness of plant stems is the outcome of the activity of the lateral meristems - stem cell niches called vascular cambium and cork cambium; the aim of my research is to unravel the molecular machinery behind such cambial activity, specification and differentiation of cells derived from the cambium. A sophisticated understanding of the molecular mechanisms and networks that control plant secondary xylem differentiation is essential to achieve continued improvement in wood biomass traits while minimizing unwanted side effects. Several regulatory genes and hormones have been implicated in the developmental stages of xylem development, such as auxin, cytokinin and recently we have proposed that thermospermine is a novel plant growth regulator with a very specific role in xylem differentiation.
Research Interests
Papers共 18 篇Author StatisticsCo-AuthorSimilar Experts
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Mikko Luomaranta, Carolin Grones, Shruti Choudhary,Ana Milhinhos, Teitur Ahlgren Kalman,Ove Nilsson,Kathryn M Robinson, Nathaniel R Street,Hannele Tuominen
The New phytologist (2024)
Concepts and Strategies in Plant SciencesPlant microRNAspp.143-168, (2020)
Anna Thamm, Sabina Sanegre-Sans, Jennifer Paisley, Susana Meader,Ana Milhinhos,Sonia Contera,Javier Agusti
ROYAL SOCIETY OPEN SCIENCEno. 3 (2019): 190126-190126
user-5ebe3c75d0b15254d6c50b36(2019)
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Author Statistics
#Papers: 19
#Citation: 263
H-Index: 9
G-Index: 16
Sociability: 5
Diversity: 0
Activity: 0
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