Pointon Amy - Innovative Medicines and Early Development, AstraZeneca R&D, Macclesfield SK10 4TG, UK Amy.Pointon@astrazeneca.com.

Pelin L Candarlioglu,Louise Delsing, Lauren Gauthier, Lauren Lewis, George Papadopoulos, May Freag,Tom S Chan,Kimberly A Homan,Mick D Fellows,Amy Pointon, Kyle Kojala

ALTEXno. 3 (2024): 469-484

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Anticancer drugs and cardiotoxicity: the role of cardiomyocyte and non-cardiomyocyte cells

Chrysa Koukorava,Chrysa Koukorava, Katie Ahmed, Shrouq Almaghrabi,Amy Pointon,Malcolm Haddrick,Michael J. Cross,Michael J. Cross

Frontiers in Cardiovascular Medicine (2024)

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Computational approaches identify a transcriptomic fingerprint of drug-induced structural cardiotoxicity

Victoria P W Au Yeung,Olga Obrezanova, Jiarui Zhou,Hongbin Yang, Tara J Bowen, Delyan Ivanov, Izzy Saffadi, Alfie S Carter, Vigneshwari Subramanian, Inken Dillmann, Andrew Hall, Adam Corrigan,

Cell biology and toxicologyno. 1 (2024): 50-50

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Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics

Tara J. Bowen,Andrew D. Southam, Andrew R. Hall,Ralf J. M. Weber,Gavin R. Lloyd,Ruth Macdonald,Amanda Wilson,Amy Pointon,Mark R. Viant

Nature Communicationsno. 1 (2023): 1-18

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Prediction of inotropic effect based on calcium transients in human iPSC-derived cardiomyocytes and machine learning

Hongbin Yang,Olga Obrezanova,Amy Pointon,Will Stebbeds,Jo Francis,Kylie A Beattie,Peter Clements,James S Harvey,Graham F Smith,Andreas Bender

Toxicology and Applied Pharmacology（2023）

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Investigating signaling mechanisms of structural cardiotoxicity via in situ single cell analysis by TOBis IMC on heterocellular cardiac organoids

Fei Guo, Andew Hall,Stephanie Ling,Christopher Tape,Amy Pointon

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY（2022）

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Deriving waveform parameters from calcium transients in human iPSC-derived cardiomyocytes to predict cardiac activity with machine learning

Hongbin Yang,Will Stebbeds,Jo Francis,Amy Pointon,Olga Obrezanova,Kylie A Beattie,Peter Clements,James S Harvey,Graham F Smith,Andreas Bender

Stem cell reports（2022）

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