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Bio
Research Interests
The Smith Group focuses on three principal research areas: (A) development of innovative synthetic methods having wide application; (B) validation of the synthetic tactics for the rapid construction of architecturally complex natural and unnatural products possession significant bio-regulatory properties, and (C) novel bioorganic/medicinal chemistry programs, including programs on neurodegeneration (Alzheimer’s and tauopathologies), in collaboration with Professors Virginia Lee and John Trojanowski (University of Pennsylvania School of Medicine), studies to inhibit both HIV-1 cellular entry and propagation in infected cells (an NIH funded Program Project, involving colleagues at Harvard, Columbia, Drexel, Yale, and Montreal: see Smith News), as well as projects on peptide/protein folding with the late Professor Robin Hochstrasser and now with Feng Gai (Penn Chemistry). In each of the collaborative programs, Smith and his students exploit the power of “state-of-the-art” organic synthesis to provide solutions to biomedical programs of importance for the improvement of human health.
The Smith Group focuses on three principal research areas: (A) development of innovative synthetic methods having wide application; (B) validation of the synthetic tactics for the rapid construction of architecturally complex natural and unnatural products possession significant bio-regulatory properties, and (C) novel bioorganic/medicinal chemistry programs, including programs on neurodegeneration (Alzheimer’s and tauopathologies), in collaboration with Professors Virginia Lee and John Trojanowski (University of Pennsylvania School of Medicine), studies to inhibit both HIV-1 cellular entry and propagation in infected cells (an NIH funded Program Project, involving colleagues at Harvard, Columbia, Drexel, Yale, and Montreal: see Smith News), as well as projects on peptide/protein folding with the late Professor Robin Hochstrasser and now with Feng Gai (Penn Chemistry). In each of the collaborative programs, Smith and his students exploit the power of “state-of-the-art” organic synthesis to provide solutions to biomedical programs of importance for the improvement of human health.
Research Interests
Papers共 1112 篇Author StatisticsCo-AuthorSimilar Experts
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Alexandra Tauzin,Lorie Marchitto, Étienne Bélanger,Mehdi Benlarbi,Guillaume Beaudoin-Bussières,Jérémie Prévost,Derek Yang,Ta-Jung Chiu,Hung-Ching Chen,Catherine Bourassa,Halima Medjahed, Marek K Korzeniowski,
medRxiv : the preprint server for health sciences (2024)
iScienceno. 7 (2024): 110141-110141
Journal of virologyno. 11 (2023): e0117123-e0117123
Virusesno. 5 (2023)
Seth H Pincus, Megan Stackhouse,Connie Watt,Kelli Ober, Frances M Cole,Hung-Ching Chen,Amos B Smith Iii,Tami Peters
Jiaming Ding,Amos B Smith
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