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个人简介
I am a bioinformatician experienced in inferring genome architecture and function using high-throughput DNA and RNA datasets.
I started by studying embedded transposable elements (‘selfish genes’) in the human transcriptome.
From there I have moved to studying ‘selfish cells’ (tumours) during post-doctoral research.
I have recently joined the Buczacki lab at the Old Road campus in Oxford, who are studying cellular organoid models of colorectal cancers. My work here would involve deciphering tumour evolution in the context of cell differentiation routes, mutation background and drug sensitivity, as inferred from analysis of bulk or single-cell sequencing approaches.
研究兴趣
论文共 46 篇作者统计合作学者相似作者
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
Scientific Reportsno. 1 (2022)
C. Domingo-Sabugo,S. A. G. Willis-Owen,A. Mandal, A. Nastase, S. Dwyer,C. Brambilla, J. Hector Galvez,Q. Zhuang,S. Popat, R. Eveleigh, M. Munter, E. Lim,
medRxiv (2021)
medRxiv (Cold Spring Harbor Laboratory) (2020)
Y. Z. Zhang, J. Hughes,A. Nastase,A. Mandal, C. Brambilla,A. Rice,J. L. Robertus,W. O. Cookson,M. F. Moffatt,A. G. Nicholson
VIRCHOWS ARCHIV (2020): S24-S24
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