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My current clinical research interests focus on innovative protocols for the treatment of childhood brain tumors, with a focus on medulloblastomas, PNET and Rhabdoid tumors (ATRT). We just completed a large study (SJMB 96) in which 162 patients were treated. We used a strategy of risk-adapted radiation therapy followed by four cycles of high-dose chemotherapy with stem cell support. We achieved very good results with this approach. Our current study (SJMB 03) opened in September 2003. In this study we are doing extensive biological studies on the tumor tissue so that we can better understand what makes a normal brain cell turn into a tumor cell. We anticipate that this information will help us find new therapies to treat high-risk tumors and allow us to safely reduce therapy in patients that we determine are low-risk patients.
Research Interests
Papers共 634 篇Author StatisticsCo-AuthorSimilar Experts
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Samuel S. Mcafee,Giles Robinson,Amar Gajjar, Nicholas S. Phillips,Silu Zhang, Ping Zou Stinnett,Ranganatha Sitaram,Darcy Raches,Heather M. Conklin,Raja B. Khan,Matthew A. Scoggins
NEURO-ONCOLOGY (2024)
Rishi R Lulla, Allen Buxton, Mark D Krailo,Margot A Lazow,Daniel R Boue,James L Leach,Tong Lin,James I Geller,Shiva Senthil Kumar,Marina N Nikiforova, Uma Chandran, Sachin S Jogal,
Neuro-Oncology Advances (2024)
Samuel S McAfee,Giles Robinson,Amar Gajjar, Nicholas S Phillips,Silu Zhang, Ping Zou Stinnett,Ranganatha Sitaram,Darcy Raches, Heather M Conklin,Raja B Khan,Matthew A Scoggins
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2024): 106669-106669
Francois Doz,Michela Casanova,Kyung-Nam Koh,Karsten Nysom,Adela Canete,Hyoung Jin Kang, Matthias Karajannis, Darren Hargrave,Nadege Corradini, Yeming Wu,Thorsten Ruf, Johannes Noe,
Cancer Researchno. 7_Supplement (2024)
crossref(2024)
Daniel C Moreira,Ibrahim Qaddoumi, Susan Spiller,Thomas W Bouldin,Alan Davidson, Nasjla Saba-Silva,Daniel V Sullivan,Ryuma Tanaka,Aaron S Wagner,Matthew Wood,Paul Klimo,Godwin Job,
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