基本信息
浏览量:3
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Research interests
Defects in innate and adaptive immunity lead to infection with a predilection for the respiratory tract, yet immune cell infiltration underpins a range of inflammatory and allergic respiratory diseases such as chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS) and asthma. To clarify the role of dysregulated immunity in these diseases, I wish to address the following questions:
How does immune cell function become deranged to promote disease pathogenesis rather than host defence?
Can we identify cellular defects that predispose to recurrent respiratory infections?
How can we use this knowledge to further diagnostic, prognostic and therapeutic interventions in diseases driven by aberrant immunity?
My current research funding encompasses the role of inappropriate neutrophil activation in COPD and ARDS, the impact of hypoxia on neutrophil function, and the role of PI3K delta in immune cell and airway biology.
研究兴趣
论文共 123 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Clare F Muir,Constantino Carlos Reyes-Aldasoro,Felix E Ellett,Tomasz K Prajsnar,Yin X Ho,Audrey Bernut,Catherine A Loynes,Stone Elworthy, Kieran A Bowden, Ashley J Cadbury,Lynne R Prince,Jason S King,
biorxiv(2024)
Amy Gilmour, Chloe Hughes, Yan Hui Giam, Rebecca C Hull, Thomas Pembridge, Hani Abo-Leyah, A A Roger Thompson,Alison M Condliffe, Amelia Shoemark,James D Chalmers, Merete B Long
ERJ open researchno. 3 (2024)
Social Science Research Network (2023): 102201-102201
Simon J. Hardman,Fiona M. Shackley,Kelechi Ugonna,Thomas C. Darton,Alan S. Rigby,Debby Bogaert, Justyna M. Binkowska,Alison M. Condliffe
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 22 (2023): 16053-16053
bioRxiv (Cold Spring Harbor Laboratory) (2023)
American Journal of Respiratory and Critical Care Medicine (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn