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RESEARCH
Research within the computational structural biology group focuses on the development of reliable bioinformatics and computational approaches to predict, model and dissect biomolecular interactions at atomic level. For this, bioinformatics data, structural information and available biochemical or biophysical experimental data are combined to drive the modelling process. This is implemented and further developed in the widely used HADDOCK software for the modelling of biomolecular complexes (http://bonvinlab.org/software).
By following a holistic approach integrating various experimental information sources with computational structural biology methods we aim at obtaining a comprehensive description of the structural and dynamic landscape of complex biomolecular machines, adding the structural dimension to interaction networks and opening the route to systematic and genome-wide studies of biomolecular interactions.
研究兴趣
论文共 385 篇作者统计合作学者相似作者
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Xiaotong Xu,Alexandre M. J. J. Bonvin
BIOINFORMATICS ADVANCESno. 1 (2024): vbad191-vbad191
Journal of Molecular Biologypp.168540, (2024)
Communications biologyno. 1 (2024): 49-49
CELLno. 19 (2023): 4059-4073.e27
Felix van der Krift,Dick W. Zijlmans,Rhythm Shukla,Ali Javed,Panagiotis I. Koukos, Laura L.E. Schwarz,Elpetra P.M. Timmermans-Sprang,Peter E.M. Maas, Digvijay Gahtory, Maurits van den Nieuwboer,Jan A. Mol,Ger J. Strous,
biorxiv(2023)
Proteomicsno. 17 (2023): e2200323-e2200323
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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