基本信息
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职业迁徙
个人简介
AREA OF EXPERTISE
Chemical Toxicology: Adductomics
My work is aimed at understanding the molecular basis of the toxic events induced by chemical agents from endogenous, environmental, drug, diet and occupational exposure sources. Based on the ability to synthesize biomarker standards and develop/validate sensitive analytical methodologies, focus has been placed on the development of synthetic and mass spectrometry-based methodologies (MS) for the use of covalent adducts formed with proteins (adductomics), directed towards:
1) Risk assessment of drugs used in chronic therapies (eg. anti-HIV drugs);
2) Development of early biomarkers of chemically-induced cancers;
3) Development of diagnosis tools of diseases induced by endogenous metabolites.
研究兴趣
论文共 138 篇作者统计合作学者相似作者
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JOURNAL OF MEDICINAL CHEMISTRYno. 8 (2024): 6081-6098
Carbohydrate polymers (2024): 121880-121880
Rita P Lopes, Raquel A Ferro, Margarida Milhazes, Margarida Figueira,Maria João Caldeira,Alexandra M M Antunes,Helena Gaspar
Frontiers in pharmacology (2023): 1145140-1145140
PHARMACEUTICALSno. 2 (2023): 146-146
Inês Maximiano, Catarina Henriques,Ricardo G Teixeira,Fernanda Marques,Andreia Valente,Alexandra M M Antunes
Journal of inorganic biochemistry (2023): 112436-112436
Plants (Basel, Switzerland)no. 19 (2023): 3486-3486
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