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个人简介
The focus of the research in the laboratory is currently split into two major directions which are apparently distinct from each other with respect to the biological systems involved, their relation to the human disease, and experimental models used. However, the main idea underlying both directions is conceptually the same - to understand how endocytosis and post-endocytic trafficking regulates function(s) of the transmembrane proteins, such as receptors and transporters.
First Direction
The elucidation of the molecular mechanisms of endocytosis of growth factor receptors using a prototypic member of the family, epidermal growth factor (EGF) receptor, and analysis of the role of endocytosis in spatial and temporal regulation of signal transduction by the EGF receptor.
Second Direction
To elucidate the role of trafficking processes in the regulation of dopaminergic neurotransmission by the plasma membrane dopamine transporter (DAT).
研究兴趣
论文共 154 篇作者统计合作学者相似作者
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Tarique Bagalkot,Alexander Sorkin
eNeurono. 1 (2024)
Cassandra Small,Mary Hongying Cheng, Saron S Belay, Sarah L Bulloch,Brooke Zimmerman,Alexander Sorkin,Ethan Robert Block
The Journal of pharmacology and experimental therapeuticsno. 2 (2023): 266-273
MOLECULAR BIOLOGY OF THE CELLno. 13 (2023): ar134-ar134
bioRxiv : the preprint server for biology (2023)
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2022)
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