Alexander Gusev

基本信息

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Bio

We are quantitative geneticists working on methods to understand complex disease. Our research focuses on deciphering biological mechanisms and trait biology from genome-wide association studies; germline influences of cancer and response to therapy; and population genetics of large clinical cohorts.

Research Interests

Papers共 211 篇Author StatisticsCo-AuthorSimilar Experts

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The Germline and Somatic Origins of Prostate Cancer Heterogeneity

Takafumi N Yamaguchi,Kathleen E Houlahan,Helen Zhu,Natalie Kurganovs,Julie Livingstone,Natalie S Fox,Jiapei Yuan,Jocelyn Sietsma Penington,Chol-Hee Jung,Tommer Schwarz,Weerachai Jaratlerdsiri,Job van Riet,Peter Georgeson,Stefano Mangiola,Kodi Taraszka,Robert Lesurf,Jue Jiang,Ken Chow,Lawrence E Heisler,Yu-Jia Shiah,Susmita G Ramanand,Michael J Clarkson,Anne Nguyen,Shadrielle Melijah G Espiritu,Ryan Stuchbery,Richard Jovelin,Vincent Huang,Connor Bell,Edward O'Connor,Patrick J McCoy,Christopher M Lalansingh,Marek Cmero,Adriana Salcedo,Eva K F Chan,Lydia Y Liu, Phillip D Stricker,Vinayak Bhandari,Riana M S Bornman,Dorota H S Sendorek,Andrew Lonie,Stephenie D Prokopec,Michael Fraser,Justin S Peters,Adrien Foucal,Shingai B A Mutambirwa,Lachlan Mcintosh,Michèle Orain,Matthew Wakefield,Valérie Picard,Daniel J Park,Hélène Hovington,Michael Kerger,Alain Bergeron,Veronica Sabelnykova,Ji-Heui Seo,Mark M Pomerantz,Noah Zaitlen,Sebastian M Waszak,Alexander Gusev,Louis Lacombe,Yves Fradet,Andrew Ryan,Amar U Kishan,Martijn P Lolkema,Joachim Weischenfeldt,Bernard Têtu,Anthony J Costello,Vanessa M Hayes,Rayjean J Hung,Housheng H He,John D McPherson,Bogdan Pasaniuc,Theodorus van der Kwast,Anthony T Papenfuss,Matthew L Freedman,Bernard J Pope,Robert G Bristow,Ram S Mani,Niall M Corcoran,Jüri Reimand,Christopher M Hovens,Paul C Boutros

Cancer discoveryno. 5 (2025): 988-1017

Cited0Views0WOSBibtex

Clinico-genomic Features Predict Distinct Metastatic Phenotypes in Cutaneous Melanoma

Tyler J Aprati,Chi-Ping Day, Daniel Lee, Alexander Pan,Justin Jee,Giuseppe Tarantino,Michael P Manos, Hannah Faulkner,Marta M Holovatska,Karam Khaddour, Catherine H Feng,Kelly P Burke, Marc Glettig,Zoe Weaver Ohler,Rajaa El Meskini,F Stephen Hodi,Rizwan Haq,Alexander N Shoushtari,Nikolaus Schultz,Jeffrey J Ishizuka,Alexander Gusev, Maryclare Griffith,Kenneth L Kehl,David Liu

bioRxiv the preprint server for biology (2025)

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Rare Germline Structural Variants Increase Risk for Pediatric Solid Tumors

Riaz Gillani,Ryan L Collins,Jett Crowdis,Amanda Garza,Jill K Jones,Mark Walker,Alba Sanchis-Juan,Christopher W Whelan,Emma Pierce-Hoffman,Michael E Talkowski,Harrison Brand,Kevin Haigis,Jaclyn LoPiccolo,Saud H AlDubayan,Alexander Gusev,Brian D Crompton,Katherine A Janeway,Eliezer M Van Allen

Science (New York, NY)no. 6729 (2025): eadq0071-eadq0071

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Human Plasma Proteomics Links Modifiable Lifestyle Exposome to Disease Risk

Shakson Isaac, Randall J Ellis,Alexander Gusev, Venkatesh L Murthy,Miriam S Udler,Chirag J Patel

medRxiv the preprint server for health sciences (2025)

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Polygenic Modifiers Impact Penetrance and Expressivity in Telomere Biology Disorders

Michael Poeschla, Uma P Arora, Amanda Walne, Lisa J McReynolds, Marena R Niewisch,Neelam Giri, Logan P Zeigler,Alexander Gusev, Mitchell J Machiela,Hemanth Tummala,Sharon A Savage, Vijay G Sankaran

The Journal of clinical investigation (2025)

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Functional Dissection of Complex and Molecular Trait Variants at Single Nucleotide Resolution

bioRxiv the preprint server for biology (2024)

Cited1Views0WOSBibtex

MSGene: a Multistate Model Using Genetic Risk and the Electronic Health Record Applied to Lifetime Risk of Coronary Artery Disease

Sarah M. Urbut,Ming Wai Yeung,Shaan Khurshid,So Mi Jemma Cho,Art Schuermans,Jakob German,Kodi Taraszka,Kaavya Paruchuri,Akl C. Fahed,Patrick T. Ellinor,Ludovic Trinquart,Giovanni Parmigiani,Alexander Gusev,Pradeep Natarajan

NATURE COMMUNICATIONSno. 1 (2024)

Cited1Views0WOSNATUREBibtex

Heterogeneous Genetic Architectures of Prostate Cancer Susceptibility in Sub-Saharan Africa

Rohini Janivara,Wenlong C. Chen,Ujani Hazra,Shakuntala Baichoo,Ilir Agalliu,Paidamoyo Kachambwa, Corrine N. Simonti, Lyda M. Brown, Saanika P. Tambe,Michelle S. Kim,Maxine Harlemon,Mohamed Jalloh, Dillon Muzondiwa, Daphne Naidoo,Olabode O. Ajayi,Nana Yaa Snyper,Lamine Niang,Halimatou Diop,Medina Ndoye,James E. Mensah,Afua O. D. Abrahams,Richard Biritwum,Andrew A. Adjei,Akindele O. Adebiyi,Olayiwola Shittu,Olufemi Ogunbiyi,Sikiru Adebayo,Maxwell M. Nwegbu,Hafees O. Ajibola,Olabode P. Oluwole,Mustapha A. Jamda,Audrey Pentz,Christopher A. Haiman,Petrus V. Spies,Andre van der Merwe,Michael B. Cook,Stephen J. Chanock,Sonja I. Berndt,Stephen Watya,Alexander Lubwama,Mazvita Muchengeti,Sean Doherty,Natalie Smyth,David Lounsbury,Brian Fortier,Thomas E. Rohan,Judith S. Jacobson,Alfred I. Neugut,Ann W. Hsing,Alexander Gusev,Oseremen I. Aisuodionoe-Shadrach,Maureen Joffe,Ben Adusei,Serigne M. Gueye,Pedro W. Fernandez,Jo Mcbride,Caroline Andrews,Lindsay N. Petersen,Joseph Lachance,Timothy R. Rebbeck

NATURE GENETICS（2024）

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Rare Germline Structural Variants Increase Risk for Pediatric Solid Tumors

Riaz Gillani,Ryan L Collins,Jett Crowdis,Amanda Garza,Jill K Jones,Mark Walker,Alba Sanchis-Juan, Chris Whelan,Emma Pierce-Hoffman,Michael Talkowski,Harrison Brand,Kevin Haigis,Jaclyn LoPiccolo,Saud H AlDubayan,Alexander Gusev,Brian D Crompton, Katie A Janeway,Eliezer M Van Allen

bioRxiv the preprint server for biology (2024)

Cited0Views0WOSBibtex

Multimodal Analysis of RNA Sequencing Data Powers Discovery of Complex Trait Genetics

Daniel Munro,Nava Ehsan,Seyed Mehdi Esmaeili-Fard,Alexander Gusev,Abraham A. Palmer,Pejman Mohammadi

NATURE COMMUNICATIONSno. 1 (2024)

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Associate Professor

Papers共 211 篇Author StatisticsCo-AuthorSimilar Experts