基本信息
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Career Trajectory
Bio
Alex’s research has contributed significantly to defining the ligands for orphan immunoreceptors and how these receptor signal in innate immune cells to evoke functional immune responses. Alex provided the first evidence that natural killer cells have evolved receptors to sense growth factors expressed by cancer cells in order to control tumour growth. Alex’s work is also relevant to infectious disease since many pathogens encode their own growth factors. Alex was the recipient of a prestigious Marie Curie International Fellowship and has published in leading scientific journals, such as Cell, Nature Immunology, Journal of Clinical Investigation and Current Opinion in Immunology.
Research Interests
Papers共 34 篇Author StatisticsCo-AuthorSimilar Experts
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Jinchao Hou, Yun Chen,Zhangying Cai,Gyu Seong Heo,Carla M. Yuede, Zuoxu Wang, Kent Lin,Fareeha Saadi,Tihana Trsan,Aivi T. Nguyen,Eleni Constantopoulos,Rachel A. Larsen,
SCIENCE TRANSLATIONAL MEDICINEno. 741 (2024): eadj9052-eadj9052
JOURNAL OF IMMUNOLOGYno. 3 (2024)
Pathogensno. 4 (2023): 572-572
BIOINFORMATICSno. 12 (2023)
Cancer Immunology, Immunotherapyno. 7 (2021): 1811-1820
Alexander James Sedgwick,Nazanin Ghazanfari, Patrick Constantinescu,Theo Mantamadiotis,Alexander David Barrow
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Author Statistics
#Papers: 37
#Citation: 3754
H-Index: 25
G-Index: 37
Sociability: 5
Diversity: 0
Activity: 0
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