基本信息
浏览量:2
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Alex Rowe is a parasite biologist and malariologist who studies both humans and parasites to try to understand why malaria is a life-threatening disease in some cases, but not others. Her research has identified key adhesion interactions between parasites and human cells that underlie the development of severe malaria by causing obstruction to blood flow in small blood vessels. She has identified human genetic factors (blood groups such as blood group O and the Knops blood group) and parasite virulence factors (adhesion molecules) that interact to influence the risk of severe and fatal malaria. Her current research uses CRISPR-Cas9 genome editing to pinpoint the molecular interactions underlying life-threatening malaria and to explore the potential for drugs or vaccines to prevent severe disease.
Alex initially trained as a doctor, and became fascinated by host-parasite interactions after attending a seminar in medical school describing how blood disorders, such as sickle cell trait and thalassaemia, protect against malaria. After a D. Phil. in Oxford, she was awarded a Wellcome Trust travelling fellowship to work at the National Institutes of Health, USA, and she established a group in Edinburgh in 1998. Honours and awards include 4 successive Wellcome Trust Fellowships, a Personal Chair in Molecular Medicine at the University of Edinburgh in 2009, the 2014 C.A. Wright medal from the British Society for Parasitology for contributions to parasitology research, and election as a Fellow of the Royal Society of Biology (2019) and the Royal Society of Edinburgh (2020).
研究兴趣
论文共 104 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Molly S A Carlier,Wilfred Nyamu,Johnstone Makale,Thomas N Williams,J Alexandra Rowe,Silvia N Kariuki
The American journal of tropical medicine and hygieneno. 3 (2024): 436-443
Florence McLean, Brian R. Omondi, Nouhoum Diallo, Stanley Otoboh, Carol Kifude,Abdirahman Abdi,Rivka Lim,Thomas Otto,Ashfaq Ghumra,J. Alexandra Rowe
biorxiv(2024)
Florence E. McLean,Yvonne Azasi, Cameron Sutherland,Emmanuel Toboh,Daniel Ansong,Tsiri Agbenyega,Gordon Awandare,J. Alexandra Rowe
biorxiv(2024)
PLOS NEGLECTED TROPICAL DISEASESno. 7 (2023): e0011133-e0011133
PLoS geneticsno. 9 (2023): e1010910-e1010910
Proceedings of the National Academy of Sciences of the United States of Americano. 22 (2021)
加载更多
作者统计
#Papers: 104
#Citation: 5121
H-Index: 35
G-Index: 71
Sociability: 6
Diversity: 0
Activity: 0
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn