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个人简介
I'm currently a researcher at the Neurological Institute Carlo Besta, UO Neurology IV, Neuroimmunology and Neuromuscular diseases laboratory. I graduated in Medical, Molecular and Cellular Biotechnologies at the Vita-Salute San Raffaele University in 2007, and I obtained a Ph.D. in Neurobiology in 2013 at the University of Insubria (Varese). My research interest deal with neuroimmunology and neuromuscular diseases, with particular interest in autoimmunity and animal models of Multiple Sclerosis (EAE) and Myasthenia Gravis (EAMG). The focuses of my research activities are mainly based on: - the development of new drugs and cellular therapies for MS/MG in the animal model; - the identification of methods to counteract the breaking of self-tolerance (fusion proteins of immunogenic epitopes). - the analysis of the composition of the gut microbioma in myasthenic and multiple sclerosis patients through NGS methodologies; - the study of the role of purinergic receptors in demielination/remielination processes.
Professional skills: leadership in research projects; writing of scientific articles and projects; tutoring of students, fellows and graduate students in universities and research institutes.
Technical skills: strong expertise in molecular and cellular biology, focused on: a) primary cell cultures preparation; b) molecular analyses of neural primary cultures and of the interplay between astrocytes and microglia; c) induction of experimental models of autoimmune and neurodegenerative diseases.
Technical expertise on molecular biology and NGS methods; breeding and maintenance of transgenic colonies; anesthesia and animal health monitoring; flow cytometry, immunofluorescence microscopy and histopathology.
研究兴趣
论文共 31 篇作者统计合作学者相似作者
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Antibiotics (Basel, Switzerland)no. 6 (2024)
ANNALS OF NEUROLOGY (2023): S60-S61
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Antibiotics (Basel, Switzerland)no. 8 (2023): 1247-1247
Edgar I. Campos-Madueno,Carola Mauri,Elisa Meroni, Pablo Porragas Paseiro,Alessandra Consonni,Francesco Luzzaro,Andrea Endimiani
Brain sciencesno. 11 (2022): 1579-1579
Multiple sclerosis and related disorders (2021): 103415-103415
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