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The Balazs lab focuses on applying this understanding to developing and implementing novel technologies that engineer immunity as a means of preventing or treating infection.
In the Balazs lab, we are scientists by training and engineers at heart. We are interested in exploring all facets of the host-pathogen interaction. Our model systems include HIV-1 and SARS-CoV-2, in which we examine mechanisms of immunological protection with a primary focus on the humoral immune system. We are equally interested in unraveling fundamental principles underlying the ability of pathogens like HIV-1 and SARS-CoV-2 to escape in response to immunological pressure. We achieve this mainly through vector-mediated gene transfer of antibody specificities, advanced humanized animal models of infection, and longitudinal deep sequencing to characterize and ultimately predict pathogen evolution.
In the Balazs lab, we are scientists by training and engineers at heart. We are interested in exploring all facets of the host-pathogen interaction. Our model systems include HIV-1 and SARS-CoV-2, in which we examine mechanisms of immunological protection with a primary focus on the humoral immune system. We are equally interested in unraveling fundamental principles underlying the ability of pathogens like HIV-1 and SARS-CoV-2 to escape in response to immunological pressure. We achieve this mainly through vector-mediated gene transfer of antibody specificities, advanced humanized animal models of infection, and longitudinal deep sequencing to characterize and ultimately predict pathogen evolution.
研究兴趣
论文共 137 篇作者统计合作学者相似作者
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Anna M. Zhang, Ahmed Elmoursi,Daniel V. DiGiacomo,Baijun Zhou,Megha Tandon, Joseph S. Hong,Nancy J. Yang,Mei-Sing Ong,Anand S. Dighe,Cristhian Berrios,Mark C. Poznansky, Anthony J. Iafrate,
Journal of Allergy and Clinical Immunology: Globalno. 2 (2024): 100234-100234
Blake M. Hauser,Maya Sangesland,Evan C. Lam,Kerri J. St Denis, Maegan L. Sheehan,Mya L. Vu,Agnes H. Cheng, Sophia Sordilla, Dana Thornlow Lamson, Ahmad W. Almawi,Alejandro B. Balazs,Daniel Lingwood,
AHMED ELMOURSI, Anna Zhang,Daniel Digiacomo,Baijun Zhou,Megha Tandon, Joseph Hong,Nancy Yang,Mei-Sing Ong,Anand Dighe,Cristhian Berrios,Mark Poznansky,Anthony John Iafrate,
Journal of Allergy and Clinical Immunologyno. 2 (2024): AB245
Alex L Roederer, Yi Cao,Kerri St Denis, Maegan L Sheehan, Chia Jung Li,Evan C Lam, David J Gregory,Mark C Poznansky,A John Iafrate,David H Canaday,Stefan Gravenstein,Wilfredo F Garcia-Beltran,
medRxiv : the preprint server for health sciences (2024)
Yasin Abul, Clare Nugent, Igor Vishnepolskiy, Tiffany Wallace, Evan Dickerson, Laurel Holland, Iva Esparza, Mandi Winkis, Kazi Tanvee Wali, Philip A Chan, Rosa R Baier,Amy Recker,
medRxiv : the preprint server for health sciences (2024)
Devin Kenney, Aoife K O'Connell,Anna E Tseng, Jacquelyn Turcinovic, Meagan L Sheehan,Adam D Nitido,Paige Montanaro,Hans P Gertje,Maria Ericsson,John H Connor,Vladimir Vrbanac, Nicholas A Crossland,
bioRxiv : the preprint server for biology (2024)
Anna Zhang, AHMED ELMOURSI,Daniel Digiacomo,Baijun Zhou,Megha Tandon, Joseph Hong,Nancy Yang, Mei-Sing Ong,Anand Dighe,Cristhian Berrios,Mark Poznansky, Anthony Iafrate,
Journal of Allergy and Clinical Immunologyno. 2 (2024): AB244
Cellno. 6 (2024): 1360-1362
Nature Communicationsno. 1 (2024): 795-795
Ildefonso Sanchez Cerrillo,Olga Popova, Maria Agudo Lera,Ilya Tsukalov, Marta Calvet Mirabent, Ignacio Santos, Lucio Garcia Fraile,Patricia Fuentes, Cristina Delgado Arevalo,Juan Alcain, Nerea Sanchez Gaona, Maria Lazaro Diez,
crossref(2024)
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