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Bio
Alanna Schepartz was born and raised in New York City.
Professor Schepartz's research group is interested in questions that span the chemistry-biology continuum. We seek to establish new knowledge about the chemistry of complex cellular processes and apply this knowledge to design or discover molecules–both small and large–with unique or useful properties. We apply the tools of organic synthesis, biochemistry, biophysics, and structural, molecular, and synthetic biology in our work. Current projects focus on (1) repurposing the ribosome to biosynthesize sequence-defined chemical polymers and polyketides; (2) exploring and improving novel tools for trafficking proteins to the cytosol and nucleus for therapeutic applications; (3) understanding the mechanism by which chemical information is transported through cellular membranes; and (4) developing new probes and fluorophores to image organelle dynamics at super-resolution for highly extended times and in multiple colors.
Professor Schepartz's research group is interested in questions that span the chemistry-biology continuum. We seek to establish new knowledge about the chemistry of complex cellular processes and apply this knowledge to design or discover molecules–both small and large–with unique or useful properties. We apply the tools of organic synthesis, biochemistry, biophysics, and structural, molecular, and synthetic biology in our work. Current projects focus on (1) repurposing the ribosome to biosynthesize sequence-defined chemical polymers and polyketides; (2) exploring and improving novel tools for trafficking proteins to the cytosol and nucleus for therapeutic applications; (3) understanding the mechanism by which chemical information is transported through cellular membranes; and (4) developing new probes and fluorophores to image organelle dynamics at super-resolution for highly extended times and in multiple colors.
Research Interests
Papers共 290 篇Author StatisticsCo-AuthorSimilar Experts
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Alexandra Kent, Jacob Robins,Isaac Knudson, Jessica Vance,Alanna Schepartz, Scott Miller, Jamie Cate
Journal of Biological Chemistryno. 3 (2024)
Madeline Zoltek, Angel L. Vazquez Maldonado,Xizi Zhang,Neville Dadina,Lauren Lesiak,Alanna Schepartz
F. Aaron Cruz-Navarrete, Wezley C. Griffin,Yuk-Cheung Chan, Maxwell I. Martin,Jose L. Alejo, Ryan A. Brady,S. Kundhavai Natchiar,Isaac J. Knudson, Roger B. Altman,Alanna Schepartz, Scott J. Miller,Scott C. Blanchard
ACS CENTRAL SCIENCEno. 6 (2024): 1262-1275
NATURE CHEMICAL BIOLOGYno. 1 (2024): 15-16
Chintan Soni,Noam Prywes, Matthew Hall, Malavika A Nair,David F Savage,Alanna Schepartz,Abhishek Chatterjee
ACS central scienceno. 6 (2024): 1211-1220
Tiyaporn Tangpradabkul,Michael Palo,Jill Townley, Kenneth B. Hsu,Eterna Participants,Sarah Smaga,Rhiju Das,Alanna Schepartz
Jonathan Giudice,Daniel D Brauer,Madeline Zoltek, Angel L Vázquez Maldonado,Mark Kelly,Alanna Schepartz
bioRxiv : the preprint server for biology (2024)
ACS central scienceno. 5 (2024): 1044-1053
PROTEIN SCIENCEno. 12 (2023)
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