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His research interest is focused on cell signaling and its manipulation by bacterial protein toxins. His laboratory studies the interaction of toxins with target cells and the host receptors involved in toxin up-take and intracellular traffic. His group discovered the molecular mechanism of numerous bacterial toxins acting by ADP-ribosylation, glycosylation and deamidation of eukaryotic target proteins. Scientific aims are elucidation of the mode of actions of bacterial protein toxins as a prerequisite for development of anti-infection strategies and to use highly specific and potent toxins as pharmacological tools in cell biology and therapy.
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Papers共 788 篇Author StatisticsCo-AuthorSimilar Experts
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGYno. 5 (2024): 2529-2530
Advances in experimental medicine and biology (2024): 219-247
Journal of Biological Chemistryno. 6 (2024): 107331-107331
Natureno. 7983 (2023): 465-467
P. Papatheodorou, S. Kindig, A. Badilla-Lobo,S. Fischer,K. Aktories, E. Chaves-Olarte,C. Rodriguez,H. Barth
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The Innovationno. 4 (2022): 100261-100261
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