基本信息
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个人简介
Francis Stewart‘s work focuses on two complementary aspects of genomics, (i) mechanisms of epigenetic regulation in eukaryotic chromatin and (ii) technologies of genetic engineering.
Future Projects and Goals:
Further work on epigenetic regulators in eukaryotes will be accompanied by advanced engineering strategies to examine roles of epigenetic regulation in mammalian development, stem cells, ageing and disease.
Methodological and Technical Expertise:
Recombineering and other DNA modification methods for BAC tagging, targeting constructs, point mutations; Site-specific recombination;
Chromatin IP;
Expression Profiling;
Genome Engineering (Gene Targeting, BAC transgenesis, Transposons, TALENS, etc.)
Mouse model studies (developmental studies, engineering);
Future Projects and Goals:
Further work on epigenetic regulators in eukaryotes will be accompanied by advanced engineering strategies to examine roles of epigenetic regulation in mammalian development, stem cells, ageing and disease.
Methodological and Technical Expertise:
Recombineering and other DNA modification methods for BAC tagging, targeting constructs, point mutations; Site-specific recombination;
Chromatin IP;
Expression Profiling;
Genome Engineering (Gene Targeting, BAC transgenesis, Transposons, TALENS, etc.)
Mouse model studies (developmental studies, engineering);
研究兴趣
论文共 307 篇作者统计合作学者相似作者
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Ji Luan, Chaoyi Song, Yan Liu, Ruoting He, Ruofei Guo,Qingwen Cui,Chanjuan Jiang, Xiaochen Li, Kexin Hao,A Francis Stewart,Jun Fu,Youming Zhang,
Nature protocols (2024)
biorxiv(2023)
Maria A. Kharlamova,Manish S. Kushwah, Tobias Jörg Jachowski,Sivaraman Subramaniam,A. Francis Stewart,Philipp Kukura,Erik Schäffer
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Leading Edge of Cancer Research Symposium: Poster Session (2022)
Nucleic Acids Researchno. 4 (2021): 1993-2004
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