基本信息
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职业迁徙
个人简介
His group at the Institute for Cancer Genetics works on the genetic and molecular basis of acute lymphoblastic leukemia using a combination of genomic technologies and biochemical, structural biology and epigenetic analyses. Over the last 10 years these studies have uncovered the functions of NOTCH1 (PNAS 2006; Nat Med 2007, PNAS 2009; Nat Med 2009, Nat Med 2014, Nat Med 2015) and the TLX1 and TLX3 oncogenes (Nat Med 2010, Nat Med 2012) in the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL). In addition his group has identified and functionally characterized numerous genes somatically mutated in T-ALL (Nat Med 2007, Cancer Cell 2013, Blood 2009,Nat Genet 2010, Nat Med 2010, J Exp Med 2011, Nat Med 2012, Nat Med 2013) and in peripheral T-cell lymphomas (Nat Genet 2014, Nat Genet 2015). Major areas of interest in the Ferrando lab are the elucidation of mechanisms of clonal evolution and resistance to chemotherapy in relapsed ALL, the functional characterization of key leukemia oncogenes and tumor suppressors, and the identification of therapeutic targets and novel synergistic drug combinations for the treatment of high risk leukemias
研究兴趣
论文共 275 篇作者统计合作学者相似作者
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Cancer Researchno. 6_Supplement (2024): 564-564
Bobby B Shih, Cindy Ma, Jose R Cortes,Clara Reglero, Hannah Miller,S Aidan Quinn,Robert Albero,Anouchka P Laurent,Adam Mackey,Adolfo A Ferrando,Larisa Geskin,Teresa Palomero
The Journal of investigative dermatology (2024)
biorxiv(2024)
Jeremy B. Samon,Mireia Castillo-Martin,Michael Hadler, Alberto Ambesi-Impiobato,Elisabeth Paietta,Janis Racevskis,Peter H. Wiernik,Jacob M. Rowe, John Jakubczak,Sophia Randolph, Carlos Cordon-Cardo,Adolfo A. Ferrando
crossref(2023)
Marissa Rashkovan,Robert Albero, Francesca Gianni,Pablo Pérez-Durán, Hannah I. Miller, Adam L. Mackey,Elisabeth Paietta,Martin S. Tallman,Jacob M. Rowe,Mark R. Litzow,Peter H. Wiernik,Selina M. Luger,
openalex(2023)
INTERNATIONAL JOURNAL OF ONCOLOGYno. 5 (2023)
crossref(2023)
Kalay Bertulfo, Koen Debackere, Hannah Miller, Ryan Najac, Cindy Ma,Adolfo A. Ferrando,Teresa Palomero
Blood (2023): 2792
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