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His research employs microfluidics for high-throughput biological applications. He has developed microfluidic methods to create emulsions that consist of droplets of very precise and consistent sizes and to manipulate the processing and contents of individual droplets in different ways. The droplets are used to create micro-compartments, which can be loaded with single cells and other active materials, such as drugs, nutrients, and assay reagents. By chaining together different microdevice components, the droplets can be used as tiny "test tubes" for performing chemical and biological reactions. This allows multiple, independent reactions to take place at the rate of thousands per second, while using minuscule amounts of total reagent. Adam is using this approach for directed evolution, genetic sequencing, and cell sorting.
Research Interests
Papers共 236 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv : the preprint server for biology (2024)
TRENDS IN BIOTECHNOLOGYno. 3 (2024): 353-368
NATURE BIOTECHNOLOGY (2023)
Nature Reviews Methods Primersno. 1 (2023)
Nature Reviews Methods Primersno. 1 (2023): 1-22
Preeti Yadav, Javier Gómez Ortega,Kai-chun Chang, Sixuan Pan, Nivedita Biswas,Julia Nilsson,Xiaoyang Yin,Aritra Bhattacharyya,Kaveh Boostanpour,Tatsuya Tsukui,Dean Sheppard, Baosheng Li,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
NATURE REVIEWS METHODS PRIMERSno. 1 (2023)
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