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We now have technologies to study the antibody responses to infectious diseases in detail, and in the last couple decades we have learned antibodies are an active hub of communication across the immune system. However, we seldom ask how our endogenously produced anti-tumor antibodies (ATAb) might influence cancer progression. Why is this? The standard tale for our progression in understanding cancer immunity is that we expected the immune system could not mount a productive defense for a long time. Checkpoint inhibitors made it clear that an active response is present but halted at its last steps. Given the recent revisions to our mental model of cellular immunity, I have been working through the literature of exactly what we know about our humoral responses. I think the results indicate it is time for a renewed focus on the humoral immune response to cancers.
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论文共 79 篇作者统计合作学者相似作者
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Hyuna Kim, Anna Wirasaputra,Farnaz Mohammadi,Aritra Nath Kundu, Jennifer A. E. Esteves,Laura M. M. Heiser,Aaron S. S. Meyer,Shelly R. R. Peyton
biorxiv(2023)
crossref(2023)
Nature Reviews Bioengineeringno. 12 (2023): 972-988
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Trends in immunologyno. 5 (2023): 329-332
Anurima Majumder, Sina Hosseinian, Mia Stroud,Emma Adhikari,James J. Saller,Matthew A. Smith,Guolin Zhang, Shruti Agarwal,Marc Creixell,Benjamin S. Meyer,Fumi Kinose,Kiah Bowers,
crossref(2023)
Brian Orcutt-Jahns, Joao Rodrigues Lima Junior,Russell C Rockne, Adina Matache,Sergio Branciamore, Ethan Hung,Andrei S Rodin,Peter P Lee,Aaron S Meyer
bioRxiv : the preprint server for biology (2023)
James Monkman,Afshin Moradi, Connor O'Leary,Zhenqin Wu, Steven Hamel, David Mason,Fabian Schneider,James Robert Mansfield,Aaron Meyer, Ken O'Byrne,Arutha Kulasinghe
CANCER RESEARCHno. 7 (2023)
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