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Alex Strongin's Research Focus Tumors produce unique enzymes, which by degrading the normal tissue provide an opportunity for tumor to grow in size and metastasize. These enzymes are called matrix metalloproteinases or MMPs. MMPs are a primary target for the design of anti-cancer pharmaceuticals. Our work aims to lay the foundation from which efficient therapeutics could ultimately be derived. Dr Strongin's research is focused on the fundamental mechanisms involving MMPs in the processes of cell migration, cell proliferation and metastasis. The far-reaching goals of this pioneering research are to gain an understanding of how MMPs by cleaving the surrounding tissue and by affecting cell surface receptors govern locomotion of malignant cells. This knowledge is critical for design of efficient pharmaceuticals that may find applications in a variety of disease conditions including cancer, arthritis and stroke.
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Swathi K. Hullugundi,Jennifer Dolkas, Andrei V. Chernov,Tony L. Yaksh, Kelly A. Eddinger, Mila Angert, Glaucilene Catroli Ferreira,Alex Y. Strongin,Patrick M. Dougherty,Yan Li, Oswal Quehenberger, Aaron Armando,
Brain, Behavior, & Immunity - Health (2024): 100757-100757
Dmitri V. Rozanov,Alexei Y. Savinov,Roy Williams, Kang Liu,Vladislav S. Golubkov, Stan Krajewski,Alex Y. Strongin
crossref(2023)
Dmitri V. Rozanov,Alexei Y. Savinov,Roy Williams, Kang Liu,Vladislav S. Golubkov, Stan Krajewski,Alex Y. Strongin
crossref(2023)
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Dmitri V. Rozanov,Alexei Y. Savinov,Roy Williams, Kang Liu,Vladislav S. Golubkov, Stan Krajewski,Alex Y. Strongin
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crossref(2023)
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