He has a special interest in childhood leukaemia and cord blood transplantation. He is chair of the UK NCRI childhood leukaemia sub-group and I-BFM ALL committee. He is chief investigator of the current and previous front line childhood and infant ALL clinical trials and is involved with several research projects in this area. Until March 2017, he was programme director of the Trent Regional Paediatric Haemopoeitic Stem Cell transplant service.
He has taken a leading role in clinical trials in childhood Acute Lymphoblastic Leukaemia and haemopoietic stem cell transplantation nationally and internationally. He is Chief Investigator of several national and international phase 3 clinical trials and Principal Investigator of over 20 trials. He has 150 peer reviewed publications and am editor of a book on childhood ALL.