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个人简介
During my PhD I worked on cardiomyocyte progenitor cells (CMPCs). These cells are found in the heart and represent an endogenous progenitor-cell population. I studied their behavior in vitro, including their ability to differentiate into different cardiac cell types. After successfully setting up an in vivo model for myocardial infarction, combined with cell transplantation and MRI, I was able to show that CMPCs differentiate into cardiac tissue and enhance cardiac function when injected directly into the heart.
As a post-doc in the Biomedical-Material-SMARTCARE consortium, I investigated the differences between embryonic heart- and adult heart-derived CMPCs.
However, my true interest is trying to repair the heart from within, and I was very excited to secure a Rubicon-fellowship to work at the lab of prof. Riley in London/Oxford to explore the in vivo behavior of endogenous progenitor cells (epicardium). After my time in the UK, I received a VENI and a LUMC research fellowship, allowing me to continue my projects, and start a research group in Leiden. Currently, I study the behavior of epicardial-derived cells from different tissue sources, and the impact of these cells on cardiac repair funded by te Dutch Heart Foundation.
研究兴趣
论文共 101 篇作者统计合作学者相似作者
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H. W. Wu, M. El Ouraoui, A. L. Van Wijnwaarden,B. Mousavi Gourabi,A. M. Smits,D. Q. C. M. Barge-Schaapveld,A. A. F. De Vries, J. W. Jukema,B. P. T. Kruithof,N. Ajmone Marsan
CARDIOVASCULAR RESEARCHno. Supplement_1 (2024)
CARDIOVASCULAR RESEARCHno. Supplement_1 (2024)
Arianne van Koppen,Elsbet Pieterman, Simon Hinke,Tri Nguyen,Amélie Dendooven,Ingeborg Bajema, Harry van Goor,Anke Smits,Reinout Stoop
Nephrology Dialysis Transplantationno. Supplement_1 (2024)
Cardiovascular Researchno. Supplement_1 (2024)
FRONTIERS IN CARDIOVASCULAR MEDICINE (2024): 1379240-1379240
Cardiovascular Researchno. Supplement_1 (2024)
M. Blok,J. M. Van Gils,B. J. D. Boukens, S. M. Kielbasa, B. W. Van Schendel,J. W. Schoones,A. M. Smits,M. J. T. H. Goumans,M. C. De Ruiter,M. R. M. Jongbloed
European Heart Journalno. Supplement_2 (2023)
Journal of the American College of Cardiologyno. 8 (2023): 1933-1933
H. W. Wu,A. L. Van Wijngaarden,B. Mousavi Gourabi,A. M. Smits,D. Q. C. M. Barge-Schaapveld, A. A. F. De Vries,J. W. Jukema,B. P. T. Kruithof,N. Ajmone Marsan
European Heart Journalno. Supplement_2 (2023)
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