基本信息
浏览量:125
职业迁徙
个人简介
He is the principal investigator (PI) of the Advancing Research and Treatment for FTLD (ARTFL) Rare Disease Clinical Research Consortium, a collaborative project funded by the National Institutes of Health to create an 18-center North American research network to support the development of new therapies for FTLD. He also leads the Four Repeat Tauopathy Neuroimaging Initiative (4RTNI), a multicenter, longitudinal tau PET and biomarker study focused on PSP and CBD. He has been the PI for a variety of multicenter, randomized, placebo controlled clinical trials in FTLD spectrum disorders, including memantine for FTLD, davunetide for PSP, TPI-287 for primary and secondary tauopathies, and salsalate for PSP. In the past he has led a variety of clinical trials in FTD and PSP including a US multicenter, randomized, placebo-controlled, clinical trial of a therapeutic agent for frontotemporal dementia (memantine/Namenda®) and an international, phase 2/3, randomized, placebo-controlled trial of the microtubule stabilizing agent, davunetide (NAP, Al-108), for PSP. He is lead principle investigator for an international Phase 2 clinical trial of the tau monoclonal antibody, BIIB092, for PSP. He also leads the FTD Treatment Study Group (FTSG), a group looking to speed the development of new therapies for FTD.
研究兴趣
论文共 591 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Neurotherapeuticspp.e00321-e00321, (2024)
Niyatee Samudra,Hannah Lerner,Leslie Yack,Christine M. Walsh,Heidi E. Kirsch,Kiwamu Kudo, Claire Yballa,Renaud La Joie,Maria L. Gorno-Tempini,Salvatore Spina,William W. Seeley, Thomas C. Neylan,
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGYno. 2 (2024): 525-535
Jeffrey Sevigny, Olga Uspenskaya, Laura Dean Heckman,Li Chin Wong, Daniel A. Hatch, Ambika Tewari,Rik Vandenberghe,David J. Irwin,Dario Saracino,Isabelle Le Ber,Rebekah Ahmed,Jonathan D. Rohrer,
Nature Medicine (2024)
Brain : a journal of neurologyno. 2 (2024): 607-626
JAMA neurologyno. 3 (2024): 295-297
Leslie S. Gaynor, Golnaz Yadollahikhales,Elena Tsoy, Matthew Hall,Adam L. Boxer,Bruce L. Miller,Lea T. Grinberg
Indira Garcia-Cordero,Chloe Anastassiadis, Abeer Khoja, Alonso Morales-Rivero,Simrika Thapa,Anna Vasilevskaya, Carly Davenport,Vishaal Sumra,Blas Couto,Namita Multani,Foad Taghdiri,Cassandra Anor,
ANNALS OF NEUROLOGY (2024)
Jean Ikanga,Sarah D. Patrick, Megan Schwinne, Saranya Sundaram Patel,Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho,Samuel Mampunza,Kevin E. Yarasheski,Charlotte E. Teunissen, Anthony Stringer,
CELLno. 6 (2024): 1565-1566
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn