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Bio
I lead the Bacterial Pathogenesis and Immunity Group at the Institute of Infection & Global Health. My area of expertise is on host pathogen interactions, in particular cellular immunity to respiratory bacterial infections. My training is in bacteriology and immunology (infection immunology), and in vivo infection modeling. My research group uses these multifaceted approaches to investigate how pathogens such as Streptococcus pneumoniae, Streptococcus pyogenes, and Pseudomonas aeruginosa cause disease and interact with host cellular immunity, in particular regulation of inflammation. To this end, we have developed clinically relevant mouse models of respiratory and systemic infection to elucidate mechanistic understanding of the disease processes involved and the host immune responses to infection. As part of these efforts, we also work on the development of novel anti-bacterial therapeutics such as phage therapy, bacterial toxin inhibitors, phagocyte activators and the development of new vaccines through the Liverpool Centre for Global Vaccine Research. My most recent publications in these fields have been in Nature Microbiology, Nature Biotechnology, Nature Communications, the AJRCCM and JACI amongst others. My research group currently consists of 11 PhD students, 5 postdocs and 2 Fellows. Our research is funded by MRC Programme and project grant, JPI-AMR funding, the Wellcome Trust and Meningitis Now, as well as by industrial partners including GSK and Roche.
Research Interests
Papers共 170 篇Author StatisticsCo-AuthorSimilar Experts
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Emma C Wall, José Afonso Guerra-Assunção,Marie Yang,Rutger Koning,Teerawit Audshasai,Alizé Proust,Rieza Aprianto,Elisa Ramos-Sevilliano,Giuseppe Ercoli,Modupeh Betts, Nicola Bordin,Vanessa S. Terra,
crossref(2024)
Yen-Linh Thi Ho,Daniel Hynes, Yuri Martina, Bill Love,Ed Horwell, Rong Xu,Aras Kadioglu,Linh Vo,Huynh A Hong, Linh Hanh Nguyen,Simon M Cutting
Journal of medical microbiologyno. 7 (2024)
Eleri A. Ashworth,Rosanna C. T. Wright,Rebecca K. Shears, Janet K. L. Wong, Akram Hassan,James P. J. Hall,Aras Kadioglu,Joanne L. Fothergill
Nature Communicationsno. 1 (2024): 1-16
Shadia Khandaker,Shilpee Sharma,Tom Hall, Suzanna Lim, Janne Lehtonen,Stephanie Leung,Andrew Gorringe,Bengt Johansson-Lindbom,Samir K. Saha,Arnaud Marchant,Kirsty Le Doare,Aras Kadioglu,
crossref(2024)
Wendy Figueroa,Adrian Cazares, Eleri Ashworth,Aaron Weimann, Rodrigo A. Floto,Aras Kadioglu,Martin Welch
crossref(2024)
Cell Reportsno. 2 (2023): 112054
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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